Electron microscopic study on the insulin-, glucagon-, somatostatin-, and pancreatic polypeptide secreting cells in Korean native goat

한국재래산양 췌장의 insulin, glucagon, somatostatin 및 pancreatic polypeptide 분비세포에 관한 전자현미경적 연구

  • Lee, Heungshik S. (College of Veterinary Medicine, Seoul National University) ;
  • Lee, In-se (College of Veterinary Medicine, Seoul National University) ;
  • Kang, Tae-cheon (College of Veterinary Medicine, Seoul National University) ;
  • Won, Moo-ho (College of Medicine, Hallym University) ;
  • Yi, Seong-joon (College of Veterinary Medicine, Kyungpook National University)
  • 이흥식 (서울대학교 수의과대학 해부학교실) ;
  • 이인세 (서울대학교 수의과대학 해부학교실) ;
  • 강태천 (서울대학교 수의과대학 해부학교실) ;
  • 원무호 (한림대학교 의과대학 해부학교실) ;
  • 이성준 (경북대학교 수의과대학 해부학교실)
  • Received : 1994.12.01
  • Published : 1995.01.31

Abstract

Ultrastructures of pancreatic endocrine cells containing glucagon, insulin, somatosratin and pancreatic polypeptide were studied in the pancreas of the Korean native goat by immunohistochemical and elecron microscopy. Glucagon immunoreatctive cells were round or fusiform in shape and contained secretory granules of 200-260 nm in diameter. The secretory granules were high in electron density and had a halo between the limiting membrane and the central granule core. Insulin immunoreactive cells were round or oval in shape, and contained various sizes of secretory granules from 135 to 300 nm in diameter. The secretory granules were low or moderate electron density and had a variform halo. Somatostatin immunoreactive cells were elliptical or fusiform shape with cytoplasmic processes. They contained the secretory granules of 140-320 nm with moderate electron densities. Pancreatic polypeptide immunoreactive cells were elliptical or fusiform and contained small secretory granules with high electron densities. The secretory granules were 120-230 nm in diameter and the least in number.

Acknowledgement

Supported by : Korea Science and Engineering Foundation