A Nonparametric Procedure for Bioassay by using Conditional Quantile Processes

  • Kim, Ho (Department of Biostatistics, University, of North Carolina, Chapel Hill, NC 27599-7499, USA.)
  • Published : 1996.12.01


Bioequivanence models arise typically in bioassays when new preparations are compared against standard ones by means of responses on some biological organisms. Relative potency measures provide nice interpretations for such bioequivalence and their estimation constitutes the prime interest of such studies. A conditional quantile process based on the k-nearest neighbor method is proposed for this purpose. An alternative procedure based on Kolmogrov-Smirnov type estimator has also been considered along with. ARIC ultrasound data are analyzed as examples.



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