Seasonal variations of the gastro-entero-pancreatic endocrine cells of the frog, Rana dybowskii

산개구리(rana dybowskii) 위장관내분비세포의 계절적 변이

  • Lee, Hyeung-sik (Department of Biology, Kyungsan University) ;
  • Lee, Jae-hyen (College of Veterinary Medicine, Kyungpook National University)
  • Received : 1995.08.18
  • Published : 1996.03.25


Comparing hibernation with active periods, the regional distribution and relative frequencies of gastrointestinal endocrine cells were studied immunohist-ochemically in the GITs of the Rana dybowskii. Six kinds of endocrine cells were identified in this study. In this study, several novel findings were emerged: in hibernation period, the perdominant presence of immunoreactive cells; the widely distributional regions of glucagon-, Gas/CCK- and BPP-immunoreactive cells; the intense reaction of immunostaining against the antiserum; and the existence of 5-HT- and somatostat-in-immunoreactive cells in upper regions of the fundic glands. These results suggest that the gastro-entero-endocrine cells in hibernation period synthesize continuously its gut hormones and accumulate in their cytoplasms.


Supported by : Korea Research Foundation