Spontaneous hemangiosarcoma in a Bengal tiger(Panthera tigris)

벵갈 호랑이에서 자연발생한 혈관육종

  • Kang, Boo-hyon (Toxicology Research Center, Korea Research Institute of Chemical Technology) ;
  • Kim, Dae-yong (Department of Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Shin, Nam-sik (Yong-In Farm Land) ;
  • Kwon, Soo-wan (Yong-In Farm Land)
  • 강부현 (한국화학연구소 스크리닝.안전성연구센터) ;
  • 김대용 (서울대학교 수의과대학 병리학교실) ;
  • 신남식 (용인자연농원) ;
  • 권수완 (용인자연농원)
  • Received : 1995.08.29
  • Published : 1996.03.25


Tumor masses from a Bengal tiger (Panthera tigris) of 13 years in age raised at the natural farm in Yong-In were examined grossly and microscopically. The tumors were observed in the subcutis, lung, heart, liver, pancreas, kidney, cecum and spleen. Histologically the tumors were composed of solid anaplastic cells that formed mature or immature small blood vessels and invaded the adjacent parenchyma. The nuclei of the tumor cells were large, vacuolated, and round or ovoid, sometimes dense and ovoid or spindle. The mitotic figures were common and the boundaries between the cells were indistinct. The stroma was very sparse. A diagnosis of this case was made as hemangiosarcoma on the basis of gross and microscopic features.