An Immunohistochemical study of the gastro-entero-pancreatic endocrine cells of the insectivorous Korean mole, Talpa micrura coreana

한국산 두더지의 위장췌내분비세포에 관한 면역조직학적 연구

  • Lee, Hyeung-sik (Department of Biology, College of Natural Science, Kyungsan University) ;
  • Lee, Jae-hyun (College of Veterinary Medicine, Kyungpook National University)
  • 이형식 (경산대학교 자연과학대학 생물학과) ;
  • 이재현 (경북대학교 수의과대학)
  • Received : 1996.02.22
  • Published : 1996.12.25

Abstract

The regional distribution and relative frequencies of the gastro-entero-pancreatic endocrine cells were studied immunohistochemically in the GIT and pancreas of the Korean mole. Seven kinds of endocrine cells were identified in this study. Although 5-HT- and somatostatin-immunoreactive cells were seen throughout the GIT, they were most predominant in the pyloric gland region. Glucagon-immunoreactive cells were restricted on the large intestine. Bovine CG-immunoreactive cells were more frequent in the stomach than in the intestines which were not detected in the duodenum. Numerous Gas/CCK-immunoreactive cells were found in the pyloric gland region, but rarely in the jejunum and ileum. BPP-immunoreactive cells were observed to be rare in the stomach and ileum but were a few in number in the intestines. In the pancreas, four types, namely, glucagon-, somatostatin-, BPP- and insulin-immunoreactive cells were identified in the pancreatic islets and exocrine portion. These results suggest that although endocrine cells of the Korean mole is less abundant in the duodenum, the distribution pattern of its gastro-entero-pancreatic endocrine cells is similar to that reported for the Korean hedgehog.