Isolation of porcine respiratory coronavirus from pig showing ataxia

보행실조증 자돈의 뇌조직에서 돼지 호흡기 코로나바이러스의 분리

  • Received : 1996.08.19
  • Published : 1997.06.25

Abstract

A cytopathogenic virus was isolated from the brain tissues of pig showing ataxia. The biophysical, morphological and serological assay showed that the isolate belongs to a coronavirus. The differential identification of the isolate with monoclonal antibodies against A and X sites of transmissible gastroenteritis virus indicated that the virus has a characteristics of porcine respiratory coronavirus. The RT-PCR on nucleocapsid region of TGEV also showed that the isolate has the same conserved sequence. The diverse pathogenesis of PRCV and its implication in field were discussed.