- Volume 30 Issue 1
Effect of Platycodon grandiflorum DC Extract on the Growth of Cancer Cell Lines
도라지(Platycodon grandiflorum DC) 추출 성분의 암세포 증식 억제효과
- Lee, Ji-Young (Graduate School of Natural Resources, and Center for Advanced Food Science and Technology, Korea University) ;
- Hwang, Woo-Ik (Department of Biochemistry, Medical College, Korea University) ;
- Lim, Seung-Taik (Graduate School of Natural Resources, and Center for Advanced Food Science and Technology, Korea University)
- Published : 1998.02.01
To investigate the cytotoxic effect of Platycodon grandiflorum DC, petroleum ether extract of Platycodon grandiflorum DC was partially purified by a silica gel column chromatography. Among several fractions, fraction D which was obtained under the elution with a 7:3 mixture of petroleum ether and ethyl ether, showed patent cytotoxicity against mouse leukemia cell line (L1210), human rectum cancer cell line (HRT-18) and human colon cancer cell lint (HCT-48).