Effect of Copper Supplementation on Mineral Utilizations in Rats

흰쥐에 있어 구리 보충이 무기질 대사에 미치는 양향

  • 최며경 (청운대학교 식품영양학과) ;
  • 전예숙 (청운대학교 식품영양학과)
  • Published : 1999.10.01


The purpose of this study was to investigate the effect of copper supplementation on mineral utilizations in rats. Intakes, excretions, and tissue levels of Fe, Zn, Cu, Ca, Mg, Na, K were compared in rats fed diet with 100, 200, 400% of copper requirement(1Cu, 2Cu and 4Cu, respectively) for 6 weeks. The feed intake was significantly higher in 2Cu compared to 1Cu group, however, body weight gain was not significantly different among the three groups. While the serum level of Fe was significantly decreased, that of Cu was significantly elevated by Cu supplementation. The liver and kidney levels of Mg and Na, intakes of all the minerals, urinary excretions of Fe, Cu, Ca and Mg were significantly higher in 2Cu and/or 4Cu compared to 1Cu. The fecal excretions, retentions and absorptions of all the minerals were not affected by Cu supple mentation. In summary, these results suggest that dietary Cu supplementation has no effect on mineral utilizations, but effect on distribution in tissues of rats.



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