Identification of Antifungal Activity Subatnces on Seedborn Disease from Garlic and Taxus Extracts

마늘, 주목의 추출물로부터 종자전염성병에 대한 항균활성물질 동정

  • Received : 1998.08.29
  • Published : 1999.02.25


Antifungal substances were isolated and identified from garlic and taxus extracts to develop safe and broad fungicide. The inhibitory effect of seedborn disease of sesame, pepper, radish, chinese cabbage by formulation of antifungal substances was investigated. The antifungal substance isolated through column chromatography from garlic and taxus extracts was confirmed by GC-MS as allicin($C_6H_{10}OS_2$) and taxol($C_{47}H_{51}NO_{14}$) and the quantified content from each extracts by HPLC analysis was 0.62%, 0.29%, respectively. The formulation composed of garlic and taxus extracts controlled effectively the seedborn fungi tested in this study at 10X dilution, but at 100X dilution the inhibitory effect decreased. Phytotoxicity of these formulations did not recognized.


antifungal activity;garlic;taxus;allicin;taxol;GC-MS;HPLC


  1. Rev. of Plant Prot. Re. v.10 P. Neagaard
  2. Rev. of Plant Prot. Re. v.10 T. Ymaguchi
  3. Bull. of Iwata-Ken Agr. Expt. Sta. v.20 S. Watanabe
  4. 농사시험연구논문집(농업산학협동) v.33 채소류 잿빛곰팡이병 방제를 위한 길항식물의 탐색과 활용기술개발(I) 白壽鳳;慶錫憲
  5. 환경환경농학회지 v.13 no.3 백수봉;경석헌;도은수;오연선;박병근
  6. J. Food Sci. v.44 A. Sharma;G. H. Tewari;A. J. Shrinkhande;S. R. Padwaldesai;C. Bandyoradyay
  7. Apple. Microbial v.17 M. G. Johnson;R. H. Vaughn
  8. Angewante, Chemie. a Journal of the Gesellschalft Deutscher chemikar v.31 B. Eric
  9. J. Am. Chem. Soc. v.67 C. J. Cavallito;J. H. Baliley;J. S. Buck
  10. Dictionary of Natural Products v.9 J. Buckingham
  11. Plant Dis. Rep. v.63 no.10 D. A. Johnson;L. E. Clark
  12. Abstr. Ann. Phytopath. Soc. Japan v.51 J. S. Park;S. Nishimura;S. Manumo;M. Katayama
  13. Ann. Phytopath. Soc. Japan. v.52 C. R. Powell;W. H. Ko
  14. Antimicrob. Agents Chemother. v.11 Y. Yamata;K. Azuma
  15. 농사시험연구논문집(농업산학협동) v.32 채소류 잿빛곰팡이병 방제를 위한 길항식물의 탐색과 활용기술개발(I) 白壽鳳
  16. Phytochemistry v.4 A. I. Virtanen
  17. Mycologia v.70 R. A. Framtling;G. S. Bulmer
  18. Proc. Assoc. Pl. Prot. Sikoku v.9 K. Ohata;C. Kubo
  19. 한국균학회지 v.17 no.1 白壽鳳
  20. Agric. Food Chem. v.19 M. H. Brondnitz;J. V. Pascale
  21. J. Amer. Oil Chem. Soc. v.55 I. G. Sumrel;R. R. Mod;F. C. Magne
  22. Science v.174 S. V. Amonker;A. Banerji


Supported by : 농촌진흥청