A study on recovery of deep hypothermia in rabbits

토끼에서 초저체온증의 회복에 관한 연구

  • Lee, Byeong-han (School of Veterinary Medicine, Kon-Kuk University) ;
  • Chun, Won-chul (School of Veterinary Medicine, Kon-Kuk University) ;
  • Kim, Jin-young (School of Veterinary Medicine, Kon-Kuk University) ;
  • Kim, Jong-sung (Department of Laboratory Animal Research, Samsung Biomedical Research Institute) ;
  • Park, Jung-hwan (Department of Laboratory Animal Research, Samsung Biomedical Research Institute) ;
  • Park, Jong-jung (Department of Laboratory Animal Research, Samsung Biomedical Research Institute) ;
  • Han, Jin-soo (Department of Laboratory Animal Research, Samsung Biomedical Research Institute) ;
  • Chung, Byung-hyun (School of Veterinary Medicine, Kon-Kuk University)
  • 이병한 (건국대학교 수의학부) ;
  • 전원철 (건국대학교 수의학부) ;
  • 김진영 (건국대학교 수의학부) ;
  • 김종성 (삼성생명과학연구소 실험동물연구실) ;
  • 박정환 (삼성생명과학연구소 실험동물연구실) ;
  • 박종성 (삼성생명과학연구소 실험동물연구실) ;
  • 한진수 (삼성생명과학연구소 실험동물연구실) ;
  • 정병현 (건국대학교 수의학부)
  • Received : 1998.08.04
  • Published : 1999.03.22

Abstract

The studies were carried out to investigate the effect of recovery in rewarming using the esophageal thermal tube in the deep hypothermia($25{\pm}1^{\circ}C$ ; rectal temp) in rabbits. Fifteen rabbits were divided into control group(n=6), peritoneal dialysis group(n=5) irrigated with dialysate at $42{\pm}1^{\circ}C$, and esophageal rewarming group(n=4) perfused with circulating water at $38{\pm}1^{\circ}C$. Rewarming of the rabbits was performed for 5 hours. MAP, HR, RR, esophageal temp, rectal temp, pH, $pCO_2$, $pO_2$, $Na^+$, and $K^+$ were observed. The results obtained in these experiments were summarized as follows : Esophageal rewarming group($38{\pm}1^{\circ}C$) had more effect on esophageal temperature than other groups. Peritoneal dialysis group($42{\pm}1^{\circ}C$) had more effect on rectal temperature and $pO_2$ than other groups. The both groups also had more effects on MAP, HR, RR, and $pCO_2$ than control group. Three groups had no significant effect on pH, $Na^+$, and $K^+$. In conclusion, we found that the simple, safe, and non-invasive esophageal rewarming method had an effect on the treatment of profound hypothermia as well as the peritoneal dialysis method in spite of the temperature difference between the dialysate and the circulating water, and the circulating water at $38{\pm}1^{\circ}C$ for esophageal rewarming also had an effect on the recovery of deep hypothermia.