Study on Bee venom and Pain

통증 관련 봉독(蜂毒) 연구에 대한 고찰(考察)

  • Yun, Hyoung-Seok (Department of Oriental Medicine Graduate school KyoungHee University) ;
  • Kim, Young-Suk (Department of Oriental Medicine Graduate school KyoungHee University) ;
  • Lee, Jae-Dong (Department of Oriental Medicine Graduate school KyoungHee University)
  • Published : 2000.07.30


In order to study Bee venom and Pain, We searched Journals and Internet. The results were as follows: 1. The domestic papers were total 13. 4 papers were published at The journal of korean acupuncture & moxibustion society, 3 papers were published at The journal of korean oriental medical society, Each The journal of KyoungHee University Oriental Medicine and The journal of korean sports oriental medical society published 1 papers and Unpublished desertations were 3. The clinical studies were 4 and the experimental studies were 9. 2. The domestic clinical studies reported that Bee venom Herbal Acupuncture therapy was effective on HIVD, Subacute arthritis of Knee Joint and Sequale of sprain. In the domestic experimental studies, 5 were related to analgesic effect of Bee vnom and 4 were related to mechanism of analgesia. 3. The journals searched by PubMed were total 18. 5 papers were published at Pain, Each 2 papers were published at Neurosci Lett. and Br J Pharmacol, and Each Eur J Pain, J Rheumatol, Brain Res, Neuroscience, Nature and Toxicon et al published 1 paper. 4. In the journals searched by PubMed, Only the experimental studies were existed. 8 papers used Bee Venom as pain induction substance and 1 paper was related to analgesic effects of Bee venom. 5. 15 webpage were searched by internet related to Bee Venom and pain. 11 were the introduction related to arthritis, 1 was the advertisement, 1 was the patient's experience, 1 was the case report on RA, 1 was review article.



  1. 봉독요법과 봉침요법 김문호
  2. 실용 의학 논문의 작성과 발표 성명훈;민양기
  3. 대한한의학회지 v.13 no.1 봉침독요법이 항염, 진통 및 해열에 미치는 효능에 관한 실험적 연구 고형균
  4. 대한침구학회지 v.15 no.2 봉독약침요법의 항염, 진통작용에 미치는 효능에 관한 실험적 연구 권기록;고형균
  5. 대한스포츠한의학회지 v.1 no.1 염좌 후유증에 대한 봉독요법의 임상 응용 권기록;고형균
  6. 대한한의학회지 v.16 no.1 흰쥐에서 합곡혈 봉독약침자극에 희한 개구반사의 반응 김이화;노식;이재동;민병일
  7. 동의병리학회지 v.8 봉독(Apitoxin)이 흰쥐의 Adjuvant 관절염에 미치는 영향 박형규;하지용;안규석
  8. 대한침구학회지 v.16 no.2 Extrusion type의 요추 추간판 탈출증 환자의 봉독요법을 병행한 한의학적 치료의 임상보고 이병철
  9. 대한침구학회지 v.16 no.3 우슬 및 봉독약침이 생쥐의 LPS유발관절염의 세포성면역반응에 미치는 영향 이승덕;김갑성
  10. 대한침구학회지 v.16 no.3 슬관절염에 대한 봉독약침의 임상적 고찰 이재동;김지훈
  11. 대한한의학회지 v.20 no.2 요추간판탈출증 환자 22례에 대한 봉독약침 치료의 요통평가지수를 이용한 임상보고 이재동;김지훈
  12. 경희한의대 논문집 v.15 중완 및 족삼리의 봉독요법이 진통효과에 미치는 영향 이종석;권기록;고형균
  13. 경희대학교 한의과대학 박사학위논문 족삼리 봉독약침자극이 Formalin-induced Pain Behavior 및 척수내 Fos 양성반응 신경세포의 활성에 미치는 영향 임윤경
  14. 경희대학교 한의과대학 박사학위논문 봉독약침이 Writhing reflex 및 척수내 통증관련 신경세포의 활성에 미치는 영향 정선희
  15. 경희대학교 한의과대학 석사학위논문 Jaw Opening Reflex 및 RT-PCR을 이용한 봉독의 진통효과 조광호
  16. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih v.13 no.4 Comparison of anti-inflammatory, analgesic activities, anaphylactogenicity and acute toxicity between bee venom and its peptides Chen, C.Y.;Chen, W.X.;Sun, X.
  17. Brain Res. v.844 no.1-2 Involvement of peripheral NMDA and non-NMDA receptors in development of persistent firing of spinal wide-dynamic-range neurons induced by subcutaneous bee venom injection in the cat Chen, J.;Li, H.;Luo, C.;Li, Z.;Zheng, J.
  18. Eur J Pain v.2 no.4 The contribution of spinal neuronal changes to development of prolonged, tonic nociceptive responses of the cat induced by subcutaneous bee venom injection Chen, J.;Luo, C.;Li, H.L.
  19. Pain v.83 no.1 Primary hyperal gesia to mechanical and heat stimuli following subcutaneous bee venom injection into the plantar surface of hindpaw in the conscious rat:a comparative study with the formalin test Chen, J.;Luo, C.;Li, Z.
  20. Pain v.84 no.2-3 Computer-assisted infrared thermographic study of axon reflex induced by intradermal melittin Koyama, N.
  21. Pain v.66 no.2-3 The bee venom test: a new tonic-pain test Lariviere, W.R.;Melzack, R.
  22. Neurosci Lett. v.285 no.2 Involvement of spinal protein kinase C in induction and maintenance of both persistent spontaneous flinching reflex and contralateral heat hyperalgesia induced by subcutaneous bee venom in the consious rat Li, K.;Zheng, J.;Chen, J.
  23. Brain Res. v.806 no.2 Spatial and temporal expression of c-Fos protein in the spinal cord of anesthetized rat induced by subcutaneous bee venom injection Luo, C.;Chen, J.(et al.)
  24. Neurosci Lett. v.278 no.1-2 Modulatory roles of the adenosine triphosphate P2x-purinoceptor in generation of the persistent nociception induced by subcutaneous bee venom injection in the conscious rat Zheng, J.H.;Chen, J,

Cited by

  1. Long-Term Effectiveness of Bee Venom Acupuncture and Physiotherapy in the Treatment of Adhesive Capsulitis: A One-Year Follow-Up Analysis of a Previous Randomized Controlled Trial vol.20, pp.12, 2014,
  2. Research about the Physical Reactions to Appear in Herbal Acupuncture Operating vol.6, pp.1, 2003,