The Study of Zn, Cu, Mn, Ni Contents of Serum, Hair, Nail and Urine for Female College Students

일부 여대생의 혈청, 소변, 두발, 손톱 중의 아연, 구리, 망간, 니켈 함량에 관한 연구

  • 승정자 (숙명여자대학교 식품영양학과) ;
  • 윤영화 (숙명여자대학교 식품영양학과)
  • Published : 2000.02.01


The purpose of this study was to evaluat the Zn, Cu, Mn and Ni status and correlation of their concentrations in serum, urine, hair and fingernail in female college students. As the results are follows; The mean age of subjects was 22.5 years and height, weight and BMI were 160.1 cm, 51.0 kg and 20.0 respectively. The daily intake of energy 1769.5 kcal and the ratio of carbohydrate, fat and protein for energy is 60 : 20 : 15. The daily intake of energy (88.5%), vitamin B2 (86.1%), Ca (75.4%), Fe (58.3%) and Zn (63.0%) of subjects did not reach to Korean Recommended Dietary Allowance (RDA). The daily mean intake of Zn, Cu, Mn and Ni were 7.56 mg, 2.30 mg, 3.81 mg and 0.18 mg respectively. The concentrations of Zn in serum, urine, hair and nail were 85.6$\mu\textrm{g}$/dL, 391.2$\mu\textrm{g}$/day, 174.6$\mu\textrm{g}$/g and 102.4$\mu\textrm{g}$/g respectively and those Cu were 84.2$\mu\textrm{g}$/dL, 56.6 $\mu\textrm{g}$/day, 20.3$\mu\textrm{g}$/g and 4.3$\mu\textrm{g}$/g respectively. The concentrations of Mn in serum, urine, hari and nail were 0.2$\mu\textrm{g}$/dL, 1.1$\mu\textrm{g}$/day, 1.8$\mu\textrm{g}$/g and 1.6$\mu\textrm{g}$/g respectively and those of Ni were 0.6$\mu\textrm{g}$/dL, 24.5$\mu\textrm{g}$/day, 3.5$\mu\textrm{g}$/g and 3.1$\mu\textrm{g}$/g respectively. The daily intake of Mn showed the positive correlations with concentration of Mn in hair (p<0.05) and the daily intake of Ni was positively correlated with urinary exretion (p<0.05) and hair contents (p<0.001) of Ni. The more detailed studies about these trace mineral status should be required.



  1. 극미량원소의 영양 승정자
  2. Present Knowledge in Nutrition (7th ed.) Robert, J.C.;Maria, C.L.
  3. Science v.21;181 no.105 Wilsom's dosease : identification of an abnormal copper-binding protein Evans, G.W.;Bubios, R.S.;Hambidge K.M.
  4. Trace element metabolism in man and animals-3. Kirchsessner, M.;Spoerl, R.;Schneider, U.A.;KirchgeBner, M.
  5. Biochemie und physiologie der Ernahrung Band I, Teil 2 KirchseBner, H.;Weigand, E.;Schnegg, A.;GraBmann, E.;Schwarz, F.J.;Roth, H.P.;Hotzel, H.D.;Kuhnau, J.
  6. Principle Clinics of North American v.27 Hair analyses Hambidge, K.M.
  7. Arch Environ Health v.26 Hair as a biopsy material-Ⅲ. Assessment of environmental lead exposure Klevay, L.M.;Hyg, S.D.;Grand, F.;
  8. Sci. Total Environ. v.31 Total mercury concentrations in human hair from 13 countries in relation to fish consumption and location Airey, D.
  9. Am. J. Clin. Nutr. v.55 Hair chromium content of women with gestational diabetes compared with nondiabeteic pregnant women Aharoni, A.;Tesler, B.;Paltieli, Y.;Tal, J.;Dori, Z.;Sharf, M.
  10. Sci. Total Environ. v.103 Monitoring of cadmum, copper, lead and zinc status in young children using toenails-comparison with scalp hair Wilhelm, M.;Hafner, D.
  11. Korean J. Nutr. v.17 A study on the zinc concentration in serum and hair of Korean female collegians Sung, C.J.
  12. Korean J. Nutr. v.31 Comparison of hair iron, zinc and copper concentrations of breast fed and formula fed infants Ahn,H.S.;Bai, H.S.
  13. Korean J. Nutr. v.32 Zinc and copper intake with food analysis and levels of zine and copper in serum, hair and urine of female college students Son, S.M.;Sung, S.I.
  14. 식품성분표 (제5개정판) 농촌진흥청 농촌생활연구소
  15. Food composition and nutrient tables Souci, S.W.;Fachmann, W.;Kraut, H.
  16. 食品微量元素含表 (第一出版) 鈴木表夫
  17. Korean J. Nutr. v.29 The relationship between dietary intakes, serum levels, urinary excretions of Zn, Cu, Fe and serum lipids in Korean rural adults on self-selected diet Lee, J.Y.;Choi, M.K.;Sung, C.J.
  18. Korean J. Nutr. v.26 Relationship among dietary intake, blood level. and urinary excretion of minerals and blood pressure in Korean rural adult men and women Sung, C.J.;Choi, M.K.;Jo, J.H.;Lee, J.Y.
  19. J. Kor. Soc. Food Nutr. v.19 The comparision of mineral intakes with serum lipids and minerals in some rural housewives Rhie, S.G.;Lee, D.T.;Kim, H.N.;Kim, A.J.;Sung, C.J.
  20. Recommenden Dietary Allowances (10th ed.) National research council
  21. Korean J. Nutr. v.26 Dietary zinc analysis and changes of zinc nutriture with zinc supplemantation in Korean adults Park, J.S.;Chyun, J.H.
  22. Assesment of the zinc nutritional status of the U.S. population based on data collection in the second National Health and Nutrition Examination Survey. 1976-1980 Pilchi, S.M.;Senti, F.R.
  23. Clin Chem. v.23 A rate nephelometer for measureing specific proteins by immunopre cipitation reactions Stenberg, J.C.
  24. Trace Elements in Human Heatlh and Disease: Zinc and Copper,Vol. 1 Homeostatic mechanims affecting plasma zinc levels in acute stress Beisel, W.R.;Pekarek, R.S.;Wannemacher, R.W.Jr.;Prasad, A.S.(ed.)
  25. Trace Elements in Humans Health and Disease: Zinc and Copper,Vol. 1 Effects of oral contraception agents on trace element metabolism: A review Smith, J.C.Jr.;Brown, E.D.;Prasad, A.D.(ed.)
  26. Principles of Nutritional Assessment Gibson, R.S.
  27. Kor. J. Nutr. v.29 Dietary copper intakes and effect of zinc supplementation on plasma copper levers in Korean adults Chyun, J.H.;Choi, Y.J.
  28. Proceed Soc. Exp. Biol. Ceruloplasmin Med. v.141 The effect of leukocytic endogenous mediator (LEM) on serum copper and concentrations in the rat Pekarek, R.S.;Powanda, M.C.;Wannemacher, R.W.Jr.
  29. Clinical Guide to Laboratory Tests Tietz, N.W.
  30. Modern Nutrition in Health and Disease (8th ed.) Shin, M.;Olson,J.A;Shike, M.
  31. Clin. Chem. v.34 Trace elements in human clinical specimans: evaluation of literature date to identify reference values Lyengar, V.;Woittiez, J.
  32. Am. J. Clin. Nutr. v.30 Tissue zinc levels and zinc excretion during experimental zinc depletion in young men Bear, M.Y.;King, J.C.
  33. Kor. J. Commu. Nutr. v.2 Zinc status of adults female in the Taegu region as assessed by dietary intake and urinary excretion Oh, H.M.;Yoon, J.S.
  34. Principles of Nutritional Assessment Gibson, R.S.
  35. Am. J. Clin. Nutr. v.32 On the assessment of zinc and copper nutriture in man Solomon, N.W.
  36. Am. J. Clin. Nutr. v.63 Copper nutrition in humans. Copper as an essential nutrient Olivares, M.;Uauy, R.
  37. J. Lab. Clin. Med. v.68 Analysis of zinc levels in hair for the diagnois of zinc deficiency in man Strain, W.H.;Steadwan, L.T.;Lankau, A.;Berliner, W.P.;Pories, W.J.
  38. Am. J. Clin. Nutr. v.33 Zinc nutrition and taste acuity in school children with impaired growth Buzina, R.;Jusic, M.;Sapunar, J.;Milanovic, N.
  39. Kor. J. Commu Nutr. v.1 The study of nutrient intake and mineral contents of hair and urine in autistic children Heo, G.Y.;Son, S.M.
  40. Akt Ernaehr. v.8 Klinish-Praktische Aspekto der zincbestimmung in humanproben Bertram, H.P.
  41. Biol. Trace Elem. Res. v.59 no.Winter Trace element contents in hair of residents from Harbin (China), Medan (Indonesia), and Tokushima (Japan) Feng, Q.;Suzuki, Y.;Hisashige, A.
  42. Pediatr. Res. v.15 The relationship of hair zinc concentration to height, weight, age and sex in the normal population Gentile, P.S.;Trentalauge, M.J.;Coleman, M.
  43. Biol. Trace Elem. Res. v.Jul. no.34 Elements in hair and nails of urban residents of New Delhi.CHD, hypertensive, and diabeticcases Sukumar, A.;Subramanian, R.
  44. Am. J. Clin. Nutr. v.31 Hair as a biopsy material V. hair metal as an index of hepatic metal in rats: Copper and zine Jacob, R.A.;Klevay, L.M.;Logan, G.M.Jr.
  45. Nut. Rep. Int. v.23 Hair as a biopsy material V1. Hari copper as an index of hepatic and kidney of rats Klevay, L.M.
  46. Biol. Trace Elem. Res. v.51 Trace elements in hair of healthy children sampled by age and sex Perrone, L.;More, R.;Caroli, M.;Toro, R.D.;Gialanella, G.
  47. Nephron. v.38 Trace element concentration in hair, fingernail and plasma of patients with chronic renal failure on (he\ modi-alysis and hemofiltration Fumiaki, M.;Yusuke, T.;Shigeru, I.;TaketoshI, K.;Seiji, Y.