Effect of Polyphenol Compounds from Persimmon Leaves (Diospyros kaki folium) on Allergic Contact Dermatitis

감잎(Diospyros kaki folium) Polyphenol 화합물군이 알레르기성 접촉피부염에 미치는 영향

  • Park, Mu-Hee (Dept. of Food Science and Technology, Yeungnam University) ;
  • Choi, Cheong (Dept. of Food Science and Technology, Yeungnam University) ;
  • Bae, Man-Jong (Faculty of Life Resources and Engineering, Kyungsan University)
  • 박무희 (영남대학교 식품가공학과) ;
  • 최청 (영남대학교 식품가공학과) ;
  • 배만종 (경산대학교 생명지원공학부)
  • Published : 2000.02.01


This study was to investigate antiallergic contact hypersensitivity of the polyphenol fractons isolated from persimmon leaves (Diospyros kaki folum). The result of the allergic contact dermatitis is a common skin disease resulting from specific immunologic sensitization due to topically applied allergens. Here the contact hypersensitivity was assayed and obdominal skin morphological changes including mast cells were examined. At contact hypersensitivity assay, less right ear swelling occured in the polyphenol fraction I, II and III groups compared to the control group. The number of mast cells was significantly decreased in the sample groups than the control group.


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