Sequential pathologic change of Korean Neospora caninum isolates in mice

Neospora caninum 국내 분리주의 경시적 변화

  • Bae, Ji-seon (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Jae-hoon (National Veterinary Research and Quarantine Service) ;
  • Lee, Jung-keun (College of Veterinary Medicine, Seoul National University) ;
  • Lee, Byung-chun (College of Veterinary Medicine, Seoul National University) ;
  • Choi, Yang-kyu (Korea Research Institute of Bioscience and Biotechnology) ;
  • Hyun, Byung-hwa (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Dae-yong (College of Veterinary Medicine, Seoul National University)
  • Received : 2000.02.25
  • Published : 2000.03.25

Abstract

This study was performed to study the sequential clinical and pathologic changes of Korean isolate KBA-2 of Neospora caninum in SCID mice following intraperitoneal infection. Also the results of PCR and in vitro isolation was compared during the study. The infection appears to be disseminated hematogenously, when the infection was chased every 3days up to 21 days following infection. The PCR method was determined to be more effective than in vitro isolation regarding early detection of the organism follwing infection.

Acknowledgement

Supported by : 농림부