Physiological Effect of Korean Black Soybean Pigment

한국산 검정콩 색소의 생리활성효과

  • Son, Jun-Ho (Department of Food Science and Tech. Yeungnam University) ;
  • Choung, Myoung-Gun (National Yeongnam Agricultural Experiment Station) ;
  • Choi, Hee-Jin (Department of Food Science and Tech. Yeungnam University) ;
  • Jang, Un-Bin (Department of Food Science and Tech. Yeungnam University) ;
  • Son, Gyu-Mok (Department of Food Nutrient, Changwon Junior College) ;
  • Byun, Myung-Woo (Team for Radiation Food Science and Biotechnology, Korea Atomic Energy Research Institute) ;
  • Choi, Cheong (Department of Food Science and Tech. Yeungnam University)
  • 손준호 (영남대학교 식품가공학과) ;
  • 정명근 (농촌진흥청 영남농업시험장) ;
  • 최희진 (영남대학교 식품가공학과) ;
  • 장운빈 (영남대학교 식품가공학과) ;
  • 손규목 (창원전문대학 식품영양과) ;
  • 변명우 (한국원자력연구소 식품.생명공학연구팀) ;
  • 최청 (영남대학교 식품가공학과)
  • Published : 2001.12.01

Abstract

Physiological effects of Korean black soybean pigment were investigated. Major anthocyanin pigments of Korean black soybean were extracted with 1% HCl for 24 hours at $4^{\circ}C$. Inhibitory effects of angiotensin converting enzyme ($IC_{50}$) were 0.22 mg/mL (Kumjungkong #1), 0.28 mg/mL (Ilpumkumjungkong) and 0.38 mg/mL (Milyang #95). Inhibitory effects xanthine oxidase ($IC_{50}$) were 0.118 mg/mL (Kumjungkong #1), 0.165 mg/mL (Ilpumkumjungkong) and 0.163 mg/mL (Milyang #95). The cPLA2 inhibitory effects ($IC_{50}$) were $19.7\;{\mu}g/mL$, $10.7\;{\mu}g/mL$ and $25.3\;{\mu}g/mL$. The cytotoxic effects of anthocyanins from Milyang #95 were 66.0% against human colon cell line (HT29), 58.2% against human liver cell line (HepG2) and 64.4% against mouse liver cell line (Hepa), respectively.