- Volume 6 Issue 2
The autoxidation reaction of L-ascorbic acid(AsA), and, particularly, the oxidation rates of AsA in the presence of Fe(III) or Cu(II) ions were determined in water and methanol. UV spectral measurement (at 265 nm) and HPLC were used to determine the remaining amounts of AsA in water and methanol, respectively. It was found that, in the presence of metal ions, the autoxidation rate of AsA was significantly affected by the kinds of solvents used, and also by the kinds of metal ions present. Moreover, the first-order rate constants for the oxidation of non-dissociated AsA compared with dissociated-AsA were investigated. It was confirmed that the oxidation of AsA was more accelerated in the dissociated form of AsA than in the non-dissociated form of AsA in either with Fe(III) or Cu(II). It was also found that the Cu(II) at a concentration of 0.1
- "Ascorbic Acid: Chemistry, Metabolism, and Uses" ACS Advances in Chemistry Series No.200 Chemistry of ascorbic acid radicals Bielski, B.H.;Seib, P.A.(ed.);Tolbert, B.M.(ed.)
- Free Radical Biol. Med. v.8 Transition metals as catalysts of "autoxidation" reactions Miller, D.M.;Buettner, G.R.;Aust, S.D.
- "Ascorbic Acid: Chemistry, Metabolism, and Uses" ACS Advances in Chemistry Series No. 200 Chelates of ascorbic acid: Formation and catalytic properties Martell, A.E.;Serb, P.A.(ed.);Tolbert, B.M.(ed.)
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- J. Agric. Food Chem. v.43 Lipid peroxidation induced by H₂O₂-activated metmyoglobin and detection of a myoglobin-derived radical Gatellier, P.;Anton, M.;Renerre, M.
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- J. Am. Chem. Soc. v.65 Oxidation processes. ⅩⅥ. The autoxidation of ascorbic acid Weissberger, A.E.;Luvalle, J.E.;Thomas, J.
- J. Am. Chem. Soc. v.65 Oxidation processes. ⅩⅦ . The autoxidation of ascorbic acid in the presence of copper Weissberger, A.E.;Luvalle, J.E.
- Can. J. Biochem. Phys. v.37 The catalysis of ascorbic acid oxidation by copper and its complexes with amino acids, peptides and proteins Scaife, J.F.
- J. Am. Chem. Soc. v.89 Metal ion and metal chelate catalyzed oxidation of ascorbic acid by molecular oxygen. Ⅰ. Cupric and ferric ion catalyzed oxidation Khan, M.M.T;Martell, A.E.
- J. Am. Chem. Soc. v.90 Kinetics of metal ion and mctal chelate catalyzed oxidation of ascorbic acid. Ⅲ. Vanadyl ion catalyzed oxidation Khan, M.M.T;Martell, A.E.
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- Free Rad. Res. Comms. v.5 Ascorbate oxidation: UV absorbance of ascorbate and ESR spectroscopy of the ascorbyl radical as assays for iron Buettner, G.R.