In Vitro Bifidogenic Effect of Nondigestible Oligosaccharides Isolated from Red Ginseng Marc

  • Published : 2001.10.01


The purpose of this research was to investigate the effects of nondigestible oligosaccharides (NDO) from red ginseng marc on the growth of Bifidobacterium spp. Red ginseng marc, a fibrous byproduct of ginseng extract from processing, was destarched by ${\alpha}$-amylase and amyloglucosidase treatment, and then treated with a commercial pectinase to produce NDO. The bifidogenic effects of NDO on B. adolescentis, B. animalis, B. breve, and B. longum were investigated in vitro. NDO significantly promoted the growth of Bifidobacterium spp. The growth, decrease of pH, and organic acid formation (acetate, lactate, formate) were markedly different among the species. B. adolescentis showed the best growth and produced the greatest amount of organic acids. When NDO was used as a carbon source in the cocultivation of Bifidobacterium spp. and Clostridium perfringens, the growth of Bifidobacterium spp. was not influenced by the existence of Cl. perfringens. The result strongly suggested that NDO from red ginseng marc could be used as a potential bifidogenic source.


  1. J. Microbiol. Biotechnol. v.7 Bifidogenic effect of glucooligosaccharide prepared from glucose by extrusion process Ahn, J. B.;J. K. Hwang;C. T.Kim;K. H. Lee;J. H. park
  2. Korean J. Ginseng Sci. v.14 Effect of Panax ginseng extract on growth response of human intestinal bacteria and bacterial metabolism Ahn, Y. J.;M. J. Kim;T. Kawamura;T. Yamamoto;T. Fujisawa;T. Mitsuoka
  3. Trends in Food science and Technology v.9 Technological aspects of functional food-related carbohydrates Alphons G. J.
  4. Anal. biochem. v.54 New method for quantitative determination of uronic acids Blumenkrantz, N.;G. Asboe-Hansen
  5. Korean J. Ginseng Sci. v.17 Comparisons of acidic polysaccharide content in various ginseng species and parts Do, J. H.;H. O. Lee;S. K. Lee;K. B. Noh;S. D. Lee;K. S. Lee
  6. Korean J. Ginseng Sci. v.20 Preparation of red ginseng extract rich in acidic polysaccharide from red tail ginseng marc produced after extraction with 70% ethyl alcohol Do, J. H.;J. W. Lee;S. K. Lee;H. S. Sung
  7. J. Nutr. v.125 Dietary modulation of the human colonic microbiota: Introducing the concept of probiotics Gibson, G. R.;M. B. Roberfroid
  8. J. Dairy Sci. v.76 Augmentation of microphage phagocytic activity by cell-free extracts of selected lactic acid-producing bacteria Glenn, E. H.;R. S. Lambrecht
  9. Modern Nutrition in Health and Disease The role of the intestinal Flora Goldin, B. R.;A. H. Lichtenstein;S. L. Gorbach;M. E. Shils(ed.);V. R. Young(ed.)
  10. Kor. J. Appl. Microbio. Bioeng. v.12 A study on the production of single cell protein from ginseng-cake extract using Saccharomyces cerevisiae Joo, H. K.;G. S. Cho
  11. FEMS Microbiol. Lett. v.182 Metabolization of β-(2,6)-linked fructose-oligosaccharides by different bifidobacteria Marx, S. P.;W. Stefaniek;H. Winfried
  12. A Color Atlas of Anaerobic Bacteria Mitsuoka, T.;T. Mitsuoka(ed.)
  13. J. Ind. Microbiol. v.6 Bifidobacteria and their role in human health Mitsuoka, T.
  14. Kor. J. Appl. Microbiol. Biotechnol. v.20 Growth effect of branched oligosaccharides on principal intestinal bacteria Park, J. H.;J. Y. Yoo;O. H. Shin;H. K. Shin;S. J. Lee;K. H. Park
  15. Bifidobacteria Microflora v.13 Induction and activation of tumorcidal cells in vivo and in vitro by the bacterial cell wall of Bifidobacterium infantis Sekine, K.;E. W. Sekine;J. Ohta;T. Tioda;T. Tatsuki;T. Kawashima;Y. Hashimoto