DOI QR코드

DOI QR Code

The Genetic and Non-Genetic Aspects of Leg Weakness and Osteochondrosis in Pigs - Review -

  • Fukawa, K. (Central Research Institute for Feed and Livestock) ;
  • Kusuhara, S. (Faculty of Agriculture, Niigata University)
  • Published : 2001.01.01

Abstract

Leg weakness in pigs is one of the most serious problems in the pig industry. Leg weakness is responsible for an increase in the rate of culling of breeding pigs, which results in economic loss in the pig industry. Many researchers have investigated the cause of leg weakness, and that of osteochondrosis, in pigs, as well as in other mammals. For evaluating leg weakness, subjective scoring criteria have been applied, but the scoring systems varied widely. Subjective scoring systems have also been used in evaluating osteochondrosis lesions in leg joints. The lesions were scored optically, radiographically and histologically. Leg weakness and osteochondrosis are to some extent heritable traits. The heritability of leg weakness and joint lesion scores was found to range from 0.01 to 0.42. Leg weakness and osteochondrosis are associated with production traits (lean percentage and back fat depth). Nutritional aspects of leg weakness and osteochondrosis have also been extensively studied. Although the energy level of the diet may affect leg weakness and osteochondrosis, other nutritional factors seem to have very little effect. Confinement conditions also have an effect on leg weakness and osteochondrosis. Although studied extensively, the cause and etiology of leg weakness and osteochondrosis remain uncertain. It could be that there are multiple causes of leg weakness.

Keywords

Leg Weakness;Osteochondrosis;Heritability;Pigs;Nutrition

Cited by

  1. The Effect of Parentage on the Prevalence, Severity and Location of Lesions of Osteochondrosis in Swine vol.51, pp.4, 2004, https://doi.org/10.1111/j.1439-0442.2004.00621.x
  2. Quantitative trait loci for leg weakness traits in a Landrace purebred population vol.81, pp.1, 2010, https://doi.org/10.1111/j.1740-0929.2009.00713.x
  3. Effects of 25-hydroxy-cholecalciferol on the development of osteochondrosis in swine vol.84, pp.4, 2012, https://doi.org/10.1111/asj.12000
  4. KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs vol.40, pp.4, 2013, https://doi.org/10.1007/s11033-012-2301-9
  5. Genome-wide QTL mapping of nine body composition and bone mineral density traits in pigs vol.46, pp.1, 2014, https://doi.org/10.1186/s12711-014-0068-2
  6. Delicate changes of bioapatite mineral in pig femur with addition of dietary xylooligosaccharide: Evidences from Raman spectroscopy and ICP vol.88, pp.11, 2017, https://doi.org/10.1111/asj.12837
  7. Associations between osteochondrosis and conformation and locomotive characteristics in pigs1 vol.90, pp.13, 2012, https://doi.org/10.2527/jas.2012-5310
  8. Gene expression profiling of articular cartilage reveals functional pathways and networks of candidate genes for osteochondrosis in pigs vol.45, pp.18, 2013, https://doi.org/10.1152/physiolgenomics.00055.2013
  9. Genetic variants of major genes contributing to phosphate and calcium homeostasis and their association with serum parameters in pigs vol.59, pp.3, 2018, https://doi.org/10.1007/s13353-018-0449-2
  10. Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs vol.15, pp.1, 2019, https://doi.org/10.1371/journal.pgen.1007759