Structure of hemolymph node in WKY rats

WKY 랫드의 혈림프절 구조

  • Park, Cheol-beom (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Seong, Je-kyung (Department of Laboratory Animal Medicine, Medical Research Center, College of Medicine, Yonsei University) ;
  • Lee, In-se (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, Heungshik S. (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Lee, Joon-sup (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Yoon, Yeo-sung (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University)
  • 박철범 (서울대학교 수의과대학) ;
  • 성제경 (연세대학교 의과대학 임상의학연구센터 실험동물부) ;
  • 이인세 (서울대학교 수의과대학) ;
  • 이흥식 (서울대학교 수의과대학) ;
  • 이준섭 (서울대학교 수의과대학) ;
  • 윤여성 (서울대학교 수의과대학)
  • Accepted : 2001.08.28
  • Published : 2001.09.25

Abstract

It has been known that the hemolymph node is one of the lymphoid organs found normally in ruminants and some rodents, and this organ shares morphological and functional characteristics of lymph node and spleen. To clanify the rigorous definition of morphological structures and functions of the hemolymph node in Wistar Kyoto(WKY)rats, we examined these organs of WKY rats gross anatomically and light microscopically. The hemolymph nodes were normally found in the abdominal cavity and in the neck of WKY rats. This organ was surrounded by a thin connective tissue capsule and there was a hilus. The parenchyma comprised a cortex of lymphatic nodules and diffuse lymphatic tissues, and a medulla of diffuse lymphatic tissues arranged in cords. Afferent and efferent lymph vessels were observed but there was no extensive subcapsular and medullary sinuses. These sinuses were filled with erythrocytes. The stroma of hemolymph nodes was composed of reticular cells and fibers, and many lymphocytes, granulocytes, erythrocytes, plasma cells, macrophages and megakaryocytes were supported by the reticular network. The above findings suggest that the hemolymph nodes of WKY rats may take part in blood formation, blood filtration and immune reaction.

Acknowledgement

Supported by : 서울대학교