Skeleton formation of mouse fetus

마우스 태자의 골격 형성

  • Kim, Bora (Dept. of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine) ;
  • Oh, Seung-hyun (Dept. of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine) ;
  • Yoon, Yeo-sung (Dept. of Laboratory Animal Medicine, Medical Research Center) ;
  • Seong, Je Kyung (Dept. of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine)
  • 김보라 (연세대학교 의과대학 임상의학연구센터) ;
  • 오승현 (연세대학교 의과대학 임상의학연구센터) ;
  • 윤여성 (서울대학교 수의과대학 조직학교실) ;
  • 성제경 (연세대학교 의과대학 임상의학연구센터)
  • Accepted : 2001.08.28
  • Published : 2001.09.25

Abstract

This study was conducted to observe the bone and cartilage formation of mouse fetuses. Mouse litters were sacrificed at pregnant 14th and 18th day and examined for gross skeletal formation using cartilage and bone staining. We identified well developed cartilage formation at the 14th pregnant day in mouse fetus. However mouse fetus at the 14th pregnant day did not show any part of bone formation. At 18th pregnant day, mouse fetus showed well developed body shape and bone and cartilage formation. This results will provide basic information for the evaluation of mouse malfromation and impairment of skeleton formation. Further study will be needed for exact explanation of bone formation from cartilage portion.