Protective effect of egg yolk antibodies in diarrhea caused by enterotoxigenic Escherichia coli 987P(F6) in early weaned pigs

조기이유자돈에 있어서 난황항체를 이용한 장독성 대장균 987P(F6) 설사증 방어효과

  • Hong, Jong-wook (Department of Animal Resource & Science, Dankook University) ;
  • Kim, In-ho (Department of Animal Resource & Science, Dankook University) ;
  • Kim, Jung-woo (Department of Animal Resource & Science, Dankook University) ;
  • Kwon, Oh-suk (Department of Animal Resource & Science, Dankook University) ;
  • Lee, Sang-hwan (Department of Animal Resource & Science, Dankook University) ;
  • Hong, Eu-chul (Department of Animal Resource & Science, Dankook University)
  • 홍종욱 (단국대학교 동물자원과학과) ;
  • 김인호 (단국대학교 동물자원과학과) ;
  • 김정우 (단국대학교 동물자원과학과) ;
  • 권오석 (단국대학교 동물자원과학과) ;
  • 이상환 (단국대학교 동물자원과학과) ;
  • 홍의철 (단국대학교 동물자원과학과)
  • Accepted : 2000.11.29
  • Published : 2001.03.20

Abstract

The protective effects of egg yolk atibodies obtained from chickens immunized with fimbrial antigens from ETEC 987P were evaluated in 14 and 21 d old pigs in which ETEC diarrhea was induced. For the Exp. 1, eight early-weaned pigs($5.00{\pm}0.5kg$ average BW and 14 d average age) and eight weaned pigs($6.00{\pm}0.5kg$ average BW and 21 d average age) were used to examine influence of egg yolk antibodies on growth performance and resistance to ETEC 987P infection. Dietary treatments included 1) administered of commercial egg yolk(14 d of age; CEY14), 2) administered of egg yolk antibodies(14 d of age; EYA14), 3) administered of commercial egg yolk(21 d of age; CEY21), 4) administered of egg yolk antibodies(21 d of age; EYA21). The 14 and 21 d old pigs were challenged with 2 ml of ETEC 987P at a dose of $10^{10}\;CFU\;ml^{-1}$ per weaned pigs. Weaned pigs treated with egg yolk antibodies recovered and pigs treated with egg yolk antibodies tended to increase average daily gain(P<0.05). Also, EYA12 and EYA21 treatments were reduced coli-form bacteria concentration and increased Lactobacilli sp. concentration from feces. For the Exp. 2, sixteen weaned pigs($6.00{\pm}0.5kg$ average daily gain BW and 21 d average age) were used to examine influence of yolk or white from egg containing antibodies on growth performance and resistance to ETEC 987P infection. Dietary treatments included l) administered of commercial egg yolk(CEY), 2) administered of commercial egg white(CEW), 3) administered of egg yolk antibodies(EYA), 4) administered of egg white antibodies(EWA). Pigs treated only with EYA showed signs of recovery. Also, EYA treatment showed the best average daily gain without significant differences (P>0.05). EYA treatment was reduced coli-form bacteria concentration increased and Lactobacilli sp. concentration from feces. In conclusion, egg yolk antibodies have protective effects from pigs in which ETEC diarrhea was induced.