A Case of Natural Mycoplasmosis in Spontaneously Hypertensive Rats

Mycoplasm pulmonis에 자연 감염된 SHR 랫드

  • Roh, In-Soon (Department of Laboratory Animal Medicine, Yonsei University College of Medicine) ;
  • Oh, Seung Hyun (Department of Laboratory Animal Medicine, Yonsei University College of Medicine) ;
  • Park, Ji Young (Department of Laboratory Animal Medicine, Yonsei University College of Medicine) ;
  • Choi, Kyung-Chul (Department of Biomedical Science, College of Veterinary Medicine, Cornell University) ;
  • Han, Jeong-Hee (Department of Veterinary Medicine, Kangwon National University) ;
  • Jin, Hee-Kyung (Department of Veterinary Medicine, Kangwon National University) ;
  • Do, Seon Gil (Experimental Animal Center, College of Medicine, Hallym University) ;
  • Suh, Jun Gyo (Experimental Animal Center, College of Medicine, Hallym University) ;
  • Oh, Yang Seok (Experimental Animal Center, College of Medicine, Hallym University) ;
  • Park, Seong-Jun (Department of Veterinary Internal Medicine, Tokyo University of Agriculture and Technology) ;
  • Seong, Je-Kyung (Department of Laboratory Animal Medicine, Yonsei University College of Medicine)
  • 노인순 (연세대학교 의과대학 임상의학연구센터 실험동물부) ;
  • 오승현 (연세대학교 의과대학 임상의학연구센터 실험동물부) ;
  • 박지영 (연세대학교 의과대학 임상의학연구센터 실험동물부) ;
  • 최경철 (코넬대학교 수의과대학 생물의학과) ;
  • 한정희 (강원대학교 동물자원대학 수의학과) ;
  • 진희경 (강원대학교 동물자원대학 수의학과) ;
  • 도선길 (한림대학교 의과대학 실험동물부) ;
  • 서준교 (한림대학교 의과대학 실험동물부) ;
  • 오양석 (한림대학교 의과대학 실험동물부) ;
  • 박성준 (동경 농공대학교 농학부) ;
  • 성제경 (연세대학교 의과대학 임상의학연구센터 실험동물부)
  • Accepted : 2001.10.28
  • Published : 2001.12.24

Abstract

Twenty one Spontaneously Hypertensive Rats(SHR) that were 4- to 21-month-old were examined histopathologically and serologically during a routine health monitoring of the rat colony. The results of the enzyme linked immunosorbent assay(ELISA) for murine pathogens demonstrated that 14 of 21 SHR rats had antibodies to Mycoplasma pulmonis. Histopathologically, the mycoplasma positive SHR rats were observed to have the typical pulmonary lesions which are characterized by the hyperplasia of the lymphoid tissue around the bronchi, bronchioles and vessels. Based on the histopathological findings and serological results, this case was diagnosed as a murine mycoplasmosis of SHR rats.