Simultaneous Analysis Method of BPA, BPF, BADGE, BFDGE and Their Degradation Products in Canned Foods and Food Simulants by HPLC

HPLC를 이용한 캔 식품 및 식품 유사용매 중 BPA, BPF, BADGE, BFDGE 및 분해산물의 동시분석법

  • Choi, Jae-Chun (Department of Applied Biology and Chemistry, KunKuK University) ;
  • Kyung, Suk-Hun (Department of Applied Biology and Chemistry, KunKuK University) ;
  • Lee, Gun-Tack (Department of Food Sciences, Kangnung National University) ;
  • Lee, Kwang-Ho (Division of Food Packaging, Korea Food and Drug Administration)
  • 최재천 (건국대학교 응용생물화학과) ;
  • 경석헌 (건국대학교 응용생물화학과) ;
  • 이근택 (강릉대학교 식품과학과) ;
  • 이광호 (식품의약품안전청 용기포장과)
  • Published : 2002.04.01

Abstract

A simple and sensitive analysis method based on reverse phase (RP) HPCL with flourescence detector was developed for simultaneous determination of bisphenol A (BPA), bisphenol F (BPF), bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE), and their degradation products, $BADGE{\cdot}H_2O$, $BADGE{\cdot}2H_2O$, $BFDGE{\cdot}H_2O$, $BFDGE{\cdot}2H_2O$, $BADGE{\cdot}HCl{\cdot}H_2O$, $BADGE{\cdot}HCl$, $BADGE{\cdot}2HCl$, $BFDGE{\cdot}HCl{\cdot}H_2O$, $BFDGE{\cdot}HCl$ and $BFDGE{\cdot}2HCl$, which were hydrolyzed and chlorinated forms of BADGE and BFDGE, in canned foods and food simulants. These compounds were identified by GC/MSD with $MSTFA-NH_4I-DTE$ derivatization. Recovery study was performed at each 100 ng/mL levels of BPA, BPF, BADGE and BFDGE added to canned foods and food simulants. This method was resulted in recovery of $90{\sim}114%$ with relative standard deviation of $4.1{\sim}7.0%$, detection limits of $6{\sim}11$ ng/mL and quantitation limits of $12{\sim}18\;ng/mL$. Calibration curves were linear with correlatin coefficients of 0.997 for BPF, 0.996 for BPA, 0.9987 for BFDGE, and 0.9989 for BADGE.

Keywords

RP HPLC;BPA;BPF;BADGE;BFDGE;$MSTFA-NH_{4}I-DTE$;canned foods;food simulants

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