Quantitative Analysis of Ethyl Carbamate in Korean Alcoholic Beverages by Chromatography with Mass Selective Detection

GC/MS 를 이용한 한국 주류 중의 Ethyl Carbamate 정량

  • Received : 2001.10.22
  • Published : 2002.02.25


In order to determine the contents of ethyl carbamate in Korean traditional alcoholic beverages and general beverages, GC/MS-SIM method was used after extraction of beverages with dichloromethane. The contents of ethyl carbamate in Korean traditional alcoholic beverages, non-distilled alcohol, and whisky were detected in the range of $4.6-50.2{\mu}g/L$, $27.8-45.4{\mu}g/L$, and $24.8-55.1{\mu}g/L$, respectively. The recoveries were ranged from 83.3 to 104.8 %. The values of relative standard deviation were ranged from 1.8 to 14.8 % and the detection limit was $0.3{\mu}g/L$.


ethyl carbamate;alcoholic beverages;gas chromatogr.;GC-MS


  1. Journal of Agricultural and Food Chemistry v.24 no.2 C.S. Ough https://doi.org/10.1021/jf60204a033
  2. Journal of Chromatography A v.369 Bailet, R.;North, D.;Myatt, D. https://doi.org/10.1016/S0021-9673(00)90115-8
  3. Journal of Chromatography A v.402 B. P. -Y. Lan;D. Weber;D. page https://doi.org/10.1016/0021-9673(87)80021-3
  4. J. Asoc. Off. Anal. Chem. v.70 Conacher. Conacher. H. B. S.;Page. B. D.;Lau, B. P. Y.;Lawrence, J. F.;Bailley, R.
  5. J. Chinese. Agric. Chem. v.35 no.1 Sansan H. W. Wagn;Sheu-Fen Chang;Gow-Chin Yen
  6. Journal of Agricultural and Food Chemistry v.24 no.2 C. S. Ough https://doi.org/10.1021/jf60204a034
  7. Journal of Agricultural and Food Chemistry v.22 no.6 G. Walker;W. Witerlin;H. Fouda;J. Seiber https://doi.org/10.1021/jf60196a007
  8. Food and Chemical Toxicology v.28 no.3 The carcinogenic potential of ethyl carbamate (urethane): Risk assessment at human dietary exposure levels Schlatter, J.;Lutz, W. K. https://doi.org/10.1016/0278-6915(90)90008-B
  9. Food Add. Contam. v.6 M. J. Dennis;N. Howarth;P. E. Key;M. Pointer abd R. C. https://doi.org/10.1080/02652038909373794
  10. J. Assoc. Off. Anal. Chem. v.60 F. L. Joe, Jr.;D. A. Kline;E.M. Miletta;J. A. G. Roach;E. L. Roseboro;T. Fazio
  11. Food Add. Conta v.7 R. Battaglia;H.G.S. Conacher;B.D.
  12. P. S. J. Natl. Cancer Inst. v.3 Nettleship, A. Henshaw
  13. ACS Symposium Series v.484 no.484 Food safety Assessment G. W. Diachenko;B. J. Canas;F. L. Joe;M. Dinovi;J. W. Finley(Ed.);S.F. Robinson(Ed.);D. J. Amstrong(Ed.) https://doi.org/10.1021/bk-1992-0484.ch034