Analysis of derivatized MX by Gas Chromatography/Mass Spectrometry

GC/MS를 이용한 MX 유도체화 분석법 연구

  • Yoo, Eun-Ah (Department of Chemistry, Sungshin Women's University) ;
  • Park, Do-Yeon (Department of Chemistry, Sungshin Women's University) ;
  • Lee, Hyang-Ki (Department of Chemistry, Sungshin Women's University) ;
  • Myung, Seung-Woon (Doping Control Center, Korea Institute of Science and Technology)
  • 유은아 (성신여자대학교 화학과) ;
  • 박도연 (성신여자대학교 화학과) ;
  • 이향기 (성신여자대학교 화학과) ;
  • 명승운 (한국과학기술연구원 도핑콘트롤센터)
  • Received : 2002.02.19
  • Published : 2002.06.25

Abstract

AMX is one of extremely high mutagenic compound produced from the reaction of the chlorine and the organic compound during the disinfection of tap water. In this paper, the chemical derivatization of MX with 2% sulfuric acid-methanol, iso-propanol, sec-butanol and n-butanol derivatives for the GC/MS analysis were tested or compared. Limit of detection for the EI and NCI mode were 25 pg and 1.25 pg, respectively. The good linear calibration curve was obtained the range of 25~2500 pg by EI and NCI

Keywords

MX;mutagenicity;GC/MS

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