Application of Dynamic Reaction Cell - Inductively Coupled Plasma Mass Spectrometry for the Determination of Calcium by Isotope Dilution Method

반응셀 유도결합플라스마 질량분석분석기를 이용한 칼슘 동위원소비율의 측정과 동위원소희석법의 적용

  • Suh, Jungkee (Division of Chemical Metrology and Materials Evaluation, Korea Research Institute of Standards and Science) ;
  • Yim, Yonghyeon (Division of Chemical Metrology and Materials Evaluation, Korea Research Institute of Standards and Science) ;
  • Hwang, Euijin (Division of Chemical Metrology and Materials Evaluation, Korea Research Institute of Standards and Science) ;
  • Lee, Sanghak (Department of Chemistry, Kyungpook National University)
  • 서정기 (한국표준과학연구원 무기분석그룹) ;
  • 임용현 (한국표준과학연구원 무기분석그룹) ;
  • 황의진 (한국표준과학연구원 무기분석그룹) ;
  • 이상학 (경북대학교 자연과학대 화학과)
  • Received : 2002.06.17
  • Published : 2002.10.25

Abstract

Inductively Coupled Plasma Dynamic Reaction Cell Quadrupole Mass Spectrometry (ICP-DRC-QMS) was characterized for the detection of the six naturally occurring calcium isotopes. The effect of the operating conditions of the DRC system was studied to get the best signal-to-noise ratio. This experiment shows that the potentially interfering ions such as $Ar^+$, ${CO_2}^+$, ${NO_2}^+$, $CNO^+$ at the calcium masses m/z 40, 42, 43, 44 and 48 were removed by flowing $NH_3$ gas at the rate of 0.7 mL/min $NH_3$ as reactive cell gas in the DRC with a RPq value (rejection parameter) of 0.6. The limits of detection for $^{40}Ca$, $^{42}Ca$, $^{43}Ca$, $^{44}Ca$, and $^{48}Ca$ were 1, 29, 169, 34, and 15 pg/mL, respectively. This method was applied to the determination of calcium in synthetic food digest samples (CCQM-P13) provided by LGC for international comparison. The isotope dilution method was used for the determination of calcium in the samples. The uncertainty evaluation was performed according to the ISO/GUM and EURACHEM guidelines. The determined mean concentration and its expanded uncertainty of calcium was ($66.4{\pm}1.2$) mg/kg. In order to assess our method, two reference samples, Riverine Water reference sample (NRCC SLRS-3) and Trace Elements in Water reference sample (NIST SRM 1643d), were analyzed.

Keywords

dynamic reaction cell;calcium isotopes;isotope dilution method;expanded uncertainty;ICP-MS;NRCC SLRS-3;NIST SRM 1643d

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