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Synthesis and Anti-inflammatory Activity of [2-(Benzothiazol-2-ylimino)-4-oxo-3-phenylthiazolidin-5-yl]-acetic Acid Derivatives

  • Sushilkumar S. Bahekar ;
  • Devanand B. Shinde
  • Published : 2003.06.20

Abstract

A synthetic method for the title compounds (2a-o) was carried out. The title compounds (2a-o)were prepared by the condensation of various thioureas and maleic anhydride. Anti-inflammatory activities in vivo were evaluated and compared with standard drug diclofenac sodium. Some compounds showed moderate activity. The structures of all the new compounds were established on the basis of $^1H$ NMR and IR spectral data.

Keywords

Anti-Inflammatory; Synthesis; [2-(Benzothiazol-2-ylimino)-4-oxo-3-phenylthiazolidin-5-yl]-acetic Acid; Thiazolidinylacetic Acid

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