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Partial Synthesis of Fibrostatins

Fibrostatins의 부분 합성

  • Kwan Hee Lee (School of Life and Food Science, Handong University) ;
  • Harold w. Moore (Department of Chemistry, Uniersity of California at Irvine)
  • 이관희 (한동대학교 생명식품과학부) ;
  • Published : 2003.02.20

Abstract

Fibrosstatins, which were isolated from the culture broth of Streptomyces catanulae subsp. griseospora, are naphthoquinones which can work as alkylating agents. It is important to synthesize these quinone compounds for the study of their biological activities. In this paper, an efficient method, Hooker oxidation, to control the regiochemistry in the synthesis of fibrostatin B is reported.

Keywords

Hook Oxidation;Fibrostatin;Allkylating Agents;Quinones

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