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Synthesis and Antibacterial Activity of Some Oxazolone Derivatives

옥사졸론 유도체의 합성과 항균성

  • Aaglawe M. J. (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • S. S. Dhule (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • S. S. Bahekar (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • P. S. Wakte (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University) ;
  • D. B. Shinde (Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University)
  • Published : 2003.04.20

Abstract

A series of oxazolone derivatives (4a-n) have been synthesized as a potential antibacterial agent. Titled compounds have been prepared by the condensation of aryloxy acetyl-amino-acetic acid with aldehyde in presence of ethanol, acetic anhydride and sodium acetate. The structures of the new compounds were established on the basis of $^1H$ NMR and IR spectral data.

Keywords

Substituted 4-Oxazol-5-One's;Antibacterial Activity;Synthesis

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