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Effects of Moschus Herbal-acupuncture on Hyperlipidemia Rats induced by Triton WR-1339

사향약침액(麝香藥鍼液)이 Triton WR-1339로 유발된 흰쥐의 고지혈증(高脂血症)에 대한 실험적(實驗的) 연구(硏究)

  • Soh, Kyung-Sun (College of Oriental Medicine, Semyung University) ;
  • Jeong, Chan-Gil (College of Oriental Medicine, Semyung University) ;
  • Kim, Kwang-Ho (Dept. of Oriental Preventive Medicine, College of Oriental Medicine, Kyunghee University) ;
  • Lee, Sang-Woon (College of Oriental Medicine, Semyung University) ;
  • Kang, Dae-In (College of Oriental Medicine, Semyung University)
  • Published : 2003.02.28

Abstract

In order to study the effects of Moschus Herbal-acupuncture on hyperlipidemia, we divided the rats into three groups(Normal group, Control group & Sample group) and performed the experimental research. Hyperlipidemia rats were induced by Triton WR-1339(150mg/kg) for 3days. Sample group was injected Moschus Herbal-acupuncture 0.1 ml/200g for 3 days and control group was injected equal dose of saline. And then we measured the amount of serum total cholesterol, triglyceride, phospholipid and HDL-cholesterol. The results were as follows : 1.Moschus Herbal-acupuncture showed decreasing effects on total cholesterol, triglyceride and phospholipid levels in serum significantly(p<0.05). 2.Moschus Herbal-acupuncture showed increasing effects on HDL-cholesterol level in serum significantly(p<0.05). According to the above results, Moschus Herbal-acupuncture showed significant decreasing effects on hyperlipidemia and it is considered that it is appropriate to apply for hyperlipidemia.

References

  1. 내과학 II 서울대학교의과대학내과학교실
  2. Harrison's Principles of Internal Medicine Eugene Braunward(外)
  3. Am J.Cardiol. v.87 Comparison of Efficacy and Safety of Atorvastatin(10mg) with Simvastatin(10mg) at Six Weeks Insull, W.;Kafonek, S.;Goldner, D.;Zieve, F.
  4. 생약학회지 v.30 한방약물로부터 항고지혈증치료약물 개발(1). 수종 한약재의 항고 지혈증 활성 검색 김남재(외)
  5. 생약학회지 v.31 no.2 한방약물로부터 항고지혈증치료약물 개발(2). 수종 한약재의 항고 지혈증 활성 검색 김남재(외)
  6. 본초학 이상인
  7. Harrison's principles of internal medicine Fauci, A.S.;Braunwald, E.;Isselbacher, K.J.;Wilson, J.D.;Martin, J.B.;Kasper, D.L.;Hauser, S.L.;Longo, D.L.
  8. Am J Hypertens v.7 Established risk factors and coronary artery disease Wilson, P.W.F. https://doi.org/10.1093/ajh/7.1.7
  9. Current Atherosclerosis Reports v.2 no.2 Cholesterol, stroke risk, and stroke prevention Ansell, B.J. https://doi.org/10.1007/s11883-000-0101-5
  10. v.17 no.1 The relationship between cholesterol and stroke: implications for antihyperlipidemic therapy in older patients Sarti, C.;Kaarisalo, M.;Tuomilehto, J. https://doi.org/10.2165/00002512-200017010-00003
  11. JAMA v.256 fro the MRFIT Reasearch Group:Is relationship between serum cholesterol and risk of premature death from coronary heart disease countinuous and graded Findings in 356,222primary screenees of the Multiple Risk Factor Intervention Trial(MRFIT) Stamler, J.;Wentworth, D.;Neaton, J.D. https://doi.org/10.1001/jama.256.20.2823
  12. 가정의학회지 v.22 no.5 高脂血症의 관리와 치료 윤방부
  13. 高脂血症的 中醫治療 陳文豈
  14. 대한한의학회지 v.18 no.1 소풍척담탕이 高脂血症에 미치는 영향 박치상;박창국;김연섭
  15. 대한한방성인병학회지 v.4 no.1 Triton WR-1339 주사로 유도된 마우스의 高脂血症에 위령탕이 미치는 영향 장효정;신길조;이원철
  16. 대한한의학회지 v.16 no.1 청심강화환이 고혈압 및 高脂血症에 미치는 영향 송미덕;고창남;조기호;김영석;배형섭;이경섭
  17. 대한동의생리학회지 v.13 no.1 혈부축어탕이 흰쥐의 실험적 高脂血症에 미치는 영향 백광현;김경철;이용태
  18. 경희한의대논문집 v.17 no.2 양의공진단이 고혈압 및 고지혈증에 미치는 영향 이용희(외)
  19. 대한한방내과학회지 v.15 no.1 사군자탕, 이진탕 및 육군자탕이 高脂血症에 미치는 영향 이승재;문병순;김세길
  20. 경희대논문집 v.18 no.2 어성초가 실험적 高脂血症의 예방에 미치는 영향 이정원;소경순;김광호
  21. 경희대논문집 v.19 no.1 상지가 실험적 高脂血症의 예방 및 치료효과에 미치는 영향 정남섭;소경순;김광호
  22. 대한본초학회지 v.14 no.1 대황이 고지혈증흰쥐의 혈중 지질 및 효소활성에 미치는 영향 손영종;김윤상;김영종
  23. 세명대논문집 흰쥐의 高脂血症에 대한 蒲黃의 예방 및 치료효과 신형섭
  24. 내과 v.81 no.2 脂質代射の調節 酒井彦;山下靜也
  25. 임상내분비학 민헌기
  26. 성인병-노인의학 서무규
  27. J. Lipid Res. v.36 Molecular physiology of reserve cholesterol transport Fielding, C.J.;Fielding, P.E.