Radiosensitizing and Antitumor Effect of the Seed of Benincasae hispida

동과자(冬瓜子)의 항암활성과 방사선에 대한 감작효과

  • 최혜란 (건국대학교 동물자원연구센터) ;
  • 이경호 (코오롱중앙연구센터) ;
  • 김창한 (건국대학교 동물자원연구센터)
  • Published : 2003.06.01

Abstract

Radiosensitizing and antitumor effects of hot water extract derived from the seed of Benincasae hispida were investigated. The extract showed maximum survival rate of 21% at 0.1 g/kg against L1210 cells implanted in BDF1 mice. Radiosensitivity of human tumor cell line was evaluated through sulforhodamine assay. Inhibition rate of SK-OV-3 cells after 5 Gy radiation by Benincasae hispida seed extract at 2 mg/mL was 86%.

Keywords

Benincasae hispida;antitumor;radiosensitivity

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