고체상 추출법을 이용한 Phthalate Esters의 분석방법 연구

DOI QR코드

DOI QR Code

홍성희;한개희;이찬형;이순화

  • 발행 : 2003.01.01

초록

The study was carried out to evaluate the new analytical method of phthalate esters(diethylphthalate, di-n-butylphthalate, butylbenzylphthalate, bis(2-ethylhexyl)phthalate), one of the endocrine disruptors, which were performed by GC/MS-SIM(selected ion monitoring). The phthalate esters were extracted from water samples using solid-phase extraction on $C_{18}$ columns. It investigated that the extraction recovery rate of phthalate esters with different solvents and solvent volume. The optimal solvent was dichloromethane and proper volume of dichloromethane for recovery of phthalate esters was 4 mL. There were good linearities(above $R^2$=0.9975) in the range 0.01~0.50mg/L, and the detection limits were below 0.01~0.03$\mu\textrm{g}$/L. The recovery rates, RSD and MDLs for phthalate esters were 80~114%, 5.0~8.1% and 0.03~0.11$\mu\textrm{g}$/L, respectively. This method shows a good precision of phthalate esters.

키워드

Phthalate esters;Endocrine disrupter;GC/MS-SIM;Solid phase extraction

참고문헌

  1. EPA, 1994, ietermination of organic compounds in drinking water by liquid-solid extraction and capillary column gas chromatography/mass spectrometry(method 525.2) EPA.
  2. 명승운, 장윤정, 민혜기, 김명수, 2000, 수질 및 저질중의 프탈산 에스테르와 아디피산 분석, 한국분석과학회지, 5(13), 616-623.
  3. 환경부, 1999, 수돗물에서의 미량유해물질 분석법 연구 및 함유실태조사(7차), 환경부.
  4. US EPA, 1996, Drinking Water Regulations and Health Advisories, EPA 822-B-96-002.
  5. IEH, 1995, Institute for Environment and Health, Leicester, UK.
  6. 국립환경연구원, 199, 내분비계장애물질의 측정분석방법, 국립환경연구원, 219-231pp.
  7. Penalver, A., E. Pocurull, F. Borrull, and R. M. Marcea., 2000, Determination of phthalate esters in water samples by solid-phase micro-extrac tion and gas chromatography with mass spectrometric detection, Journal of Chromatography A , 872(1-2), 191-201. https://doi.org/10.1016/S0021-9673(99)01284-4
  8. Jara, S., C. Lysebo, T. Greibrokk, and E. Lundanesa, 2000, Determination of phthalates in water samples using polystyrene solid-phase extraction and liquid chromatography quantification' Analytica Chimica Acta, 407(1-2), 165-171. https://doi.org/10.1016/S0003-2670(99)00829-6
  9. WHO, 1996, Guidelines for drinking-water quality(2nd ed), WHO, Geneva, 917-949pp.
  10. Amdur, Casarett, and Doul, 1991, Toxicology, The Science of Poisons, 499pp.
  11. Penalver, A., E. Pocurull, F. Borrull, and R. M. Marce, 2001, Comparison of different fibers for the solid-phase microextraction of phthalate esters from water, Journal of Chromatography, 922(1-2), 377-384. https://doi.org/10.1016/S0021-9673(01)00920-7