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Effect of Biologically Active Fractions from Onion on Physiological Activity and Lipid Metabolism

양파로부터 분리한 생리활성분획이 생리활성 및 지질대사에 미치는 영향

  • Woo, Hi-Seob (School of Food Science, Dongju College) ;
  • Aan, Bong-Jeun (Faculty of Life Resources and Engineering, Kyungsan University) ;
  • Bae, Jong-Ho (Dept. of Confectionary Decoration, Daegu Future College) ;
  • Kim, Sung (Dept. of Food Science and Technology, Yeungnam University) ;
  • Choi, Hee-Jin (Dept. of Food Science and Technology, Yeungnam University) ;
  • Han, Ho-Suk (Dept. of Food Science and Technology, Yeungnam University) ;
  • Choi, Cheong (Dept. of Food Science and Technology, Yeungnam University)
  • 우희섭 (동주대학 식품과학계열) ;
  • 안봉전 (경산대학교 생명자원공학부) ;
  • 배종호 (대구미래대학 제과데코레이션과) ;
  • 김성 (영남대학교 생물산업공학부) ;
  • 최희진 (영남대학교 생물산업공학부) ;
  • 한호석 (영남대학교 생물산업공학부) ;
  • 최청 (영남대학교 생물산업공학부)
  • Published : 2003.02.01

Abstract

From the 80% ethanol extraction of onion flesh, fraction I,II and III were separated by Sephadex LH-20 column chromatography. Fraction II and III had a high inhibitory effect on ACE and xanthine oxidase. The ACE was about 80% at 50 ppm of fraction IIand III. The xanthine oxidase was about 82.5% at 100 ppm of fraction In. This research was studied to investigate the effects of the fraction In isolated from onion on the reduction of fat accumulation in rats fed high fat diet for 2 months. The metabolism was examined by analyzing the fat in serum and liver. It was shown that cholesterol in serum was remarkably reduced in onion fraction In as compared with those of control.

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