Effects of High Amylose Starch on Lipid Metabolism and Immune Response in Rats

고아밀로오스전분의 섭취가 흰쥐의 지방대사 및 면역능력에 미치는 영향

  • 설소미 (단국대학교 식품영양학과) ;
  • 방명희 (단국대학교 식품영양학과) ;
  • 최옥숙 (단국대학교 식품영양학과) ;
  • 김우경 (단국대학교 식품영양학과)
  • Published : 2003.04.01


This study was conducted to investigate the effects of high amylose corn starch consumption on plasma, liver and feces lipid profiles and immune responses in male Sprague-Dawley rats. Experimental animals were fed on diets containing the high amylose starch (HAS,0, 125, 250,500 g/kg diet) for 4 weeks. HAS intake did not affect on food intakes and food efficiency ratio. Final body weights were lowered in HA100 group than in control group. HAS intakes dose dependently increased the weights of cecum and excretion of feces per day, and decreased the pH of cecum contents. And HAS intakes significantly decreased the plasma total lipid, triglyceride and total cholesterol levels. But there were not significant differences total lipid, triglyceride and cholesterol concentrations in liver. The absolute and relative weights of thymus and spleen, plasma Is G and $C_3$ concentrations were unaffected by experimental diets. The splenocyte proliferations with low dose Con A (0.1$\mu\textrm{g}$/10 $\mu$L) as lower in HA25 group and HA50 group than in control group. These results demonstrate that high amylose corn starch intakes significantly improve lipid profiles in plasma.


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