Synthesis and structural analysis of chromium(III) picolinate complexes

Cr(III)-picolinate 착물의 합성과 구조분석에 관한 연구

  • 김성일 ((주)이지바이오시스템 생물자원연구소) ;
  • 강대경 ((주)이지바이오시스템 생물자원연구소) ;
  • 차기원 (인하대학교 화학과)
  • Received : 2002.08.12
  • Accepted : 2003.01.15
  • Published : 2003.02.25

Abstract

Chromium(III) picolinate, a highly bioavailable compound, is known to be used for supplementing essential chromium(III) to human beings and animals. Two different methods were used to synthesize chromium(III) picolinate. The synthetic products were characterized by elemental analysis, FTI-IR, high performance liquid chromatography (HPLC) and MALDI-MS.

References

  1. Journal of Inorganic Biochemistry v.49 no.3 Composition and biological activity of chromium-pyridine carboxylate complexes G.W. Evan;D.K. Poucknik https://doi.org/10.1016/0162-0134(93)80003-R
  2. Bull. Chem. Soc.(Japan) v.41 S. Takata;E. Kyuno;R. Tsuchiya
  3. Journal of Inorganic Biochemistry v.46 no.4 Chromium picolinate increases membrane fluidity and rate of insulin internalization G.W. Evans;T.D. Bowman https://doi.org/10.1016/0162-0134(92)80034-S
  4. Harefuah A. Ravina;L. Slezack
  5. Diabetes v.46 R.A. Andeerson;N. Cheng;N. Bryden;M. Polansky;N. Cheng;J. Feng.
  6. Journal of Inorganic Biochemistry v.49 no.3 Composition and biological activity of chromium-pyridine carboxylate complexes G.W. Evans;D.J. Pouchnik https://doi.org/10.1016/0162-0134(93)80003-R
  7. (5th ed.) v.1 R.A. Anderson
  8. Ph.D. thesis. Louisiana State University T.G. Page
  9. J. Animal Science Suppl v.69 T.G. Page;T.L. Ward;L.L. Southern
  10. J. Am. Coll. Nutr. v.16 R.A. Anderson;N.A. Bryden;M.M. Polansky
  11. FASEB J. v.9 D.M. Stearns;J.P. Wise Sr.;S.R. Patierno;K.E. Wetterhahn
  12. FASEB J. v.9 D.M. Stearns;J.J. Belbruno;K.E. Wetterhahn
  13. Annals of Pharmacotherapy v.32 no.4 Chromium picolinate toxicity. J. Cerulli;D.W. Grabbe;M. Malone;M.D. McGoldrick https://doi.org/10.1345/aph.17327
  14. Inorganic Chemistry v.2 no.4 A.J. Saraceno;B.P. Block https://doi.org/10.1021/ic50008a050
  15. Inorganic Chemistry v.31 no.25 D.M. Stearns;W.H. Armstrong https://doi.org/10.1021/ic00051a007
  16. Indian J. Chem. v.20A M. Bhattacharya;G.S. De
  17. Koord. Khim. v.13 N.N Borisova;A.A. Shabilalov;M.A. Azizov
  18. Ann. Chim.(Rome) v.67 L. Campanella;E. Chiacchierini;G. De Angelis;V. Petrone
  19. Ber. v.50 H. Ley;K. Ficken
  20. Inorganic Chemistry v.2 no.4 A.J. Saraceno;B.P. Block https://doi.org/10.1021/ic50008a050
  21. Journal of Inorganic Biochemistry v.66 no.2 Characterization and Structure by NMR and FTIR Spectroscopy, and Molecular Modeling of Chromium(III) Picolinate and Nicotinate Complexes Utilized for Nutritional Supplementation C. L. Broadburst;F. Walter;Schmidt;B. James;Reeves Ⅲ;M.Marilyn;Polansky;K. Gautschi;A. Richard https://doi.org/10.1016/S0162-0134(96)00192-4
  22. Journal of Inorganic Biochemistry v.72 no.1-2 K. F. Kingry;A. C. Royer;J. B. Vincent https://doi.org/10.1016/S0162-0134(98)10067-3
  23. Polyhedron v.18 no.22 A re-investigation the electronic spectra of chromium(III) picolinate complexes and high yield synthesis and characterization of Cr2(μ-OH)2(pic)4.5H2O (H N. E. Chakov;R. A. Collins;J. B. Vincent https://doi.org/10.1016/S0277-5387(99)00208-9
  24. Analytical Chemistry v.68 no.12 Mass Spectrometry A.L. Burlingame;R.K. Boyd;S.J. Gaskell https://doi.org/10.1021/a1960021u
  25. Analytical Chemistry v.63 no.24 F. Hillenkamp;M. Karas;R. Beavis;B.T. Chait https://doi.org/10.1021/ac00024a002
  26. Anal. Chem. v.9 M. Karas;U. Bahr
  27. Int. J. Mass spectrum. Ion Processes(Special Issue) v.169;170 F. Hillenkamp(ed.)
  28. Science v.246 no.4926 J.B. Fenn;M. Mann;C.K. Meng;S.F. Wong;C.M. White-house https://doi.org/10.1126/science.2675315