Scintigraphic Evaluation of Alveolar Bone Following Dental Implantation in Dogs

개에서 치아 임플란트 식립후 치조골의 신티그라피 평가

  • Kim, Joong-hyun (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Lee, Jae-yeong (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Kim, Myoung-hwan (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Lee, Won-guk (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Kang, Seong-soo (College of Veterinary Medicine and Institute of Veterinary Medical Science, Chonnam National University) ;
  • Choi, Seok-hwa (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
  • 김중현 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 이재영 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 김명환 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 이원국 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 강성수 (전남대학교 수의과대학 및 동물의학연구소) ;
  • 최석화 (충북대학교 수의과대학 및 동물의학연구소)
  • Accepted : 2003.06.17
  • Published : 2003.06.30

Abstract

This study aimed to determine of osseointegration following dental implantation in the dog mandible using bone scintigraphy. Five mongrel dogs, weighing approximately 8.5 kg and averaging 1.8 years of age, without active periodontal disease were used. During the entire study period, all dogs were fed a soft commercial diet and water ad libitum to minimize functional loading of the implant. Titanium alloy implant systems 10 mm in length and 4 mm in diameter were chosen for insertion. Twelve weeks prior to implantation, the second and third left mandibular premolars in each dog were extracted for the dental implant insertion. Before the dental implantation procedures and 0, 4, 8, and 12 weeks after the insertions, clinical observation, radiography and bone scintigraphy were conducted. The scintigraphy was obtained using a large field of view gamma camera equipped with a paralled-hole, low-energy collimator about 3 hours after intravenous injection of Tc-99m-MDP (8 mCi/dog) to the dogs. There were not inflammation sign after insertion of dental implants on the mandible in dogs. Implants were slightly movable at the first and fourth weeks, and there was no mobility after 8 weeks. Twelve weeks after dental implantation, the bone uptake scintigraphy of peri-implant bone was similar to that of normal alveolar bone, indicating that peri-implant bone was completely regenerated by new bone. In conclusion, we recommend stable implant fixation with alveolar bone for the accurate and safe repair of teeth loot due to decacy, trauma or peridontal disease. Titanium alloy implants were optimal due to their biocompatibility.

References

  1. Baru, A. M., Garcia, M, MIranda, R., Vazquez, L., Apurido, C, Olive, J. and Lausmaa, J. Characterization of surface roudmess in Dtaimmchilal inplanls measured with scanning tunneling nicroscopy at atmospheric pressure. Biomaterials. 1986, 7(6), 463-466
  2. Branemark, P. I. Tissue integrated prosthesis. Quin-tessence Pub Co. 1985, 11-71
  3. Karagianes, M. T., Westennan, R. E., Rasmussen, J. J. and Lodmell, A. M. Development and evaluation of porous dental implants in miniature swine. J. Dent. Res. 1976, 55(1), 85-93
  4. Warshawsky, H. and Clokie, C. M. Morphologic and radioautognphic studies of bone formation in relation to titanium implants using the rat tibia as a irodel. Int. J. Oral. Maxillofacial. Implants. 1995, 10(2), 155-165
  5. Weinlaender, M. Bone growth around dental implants. Dent. Clin. N. Am. 1991, 35(3), 580-585
  6. McKinney, R. V. (ed). Endosteal dental implants. CV Mosby Co. St Louis, 1991, 3-18
  7. Ring, M. E. An illustrated history. CV Mosby Co. New York and St Louis, 1985, 22-35
  8. Linkow, L. and Rinaldi, A. The significance of 'fibro-osseous integration' and 'osseointegration' in endosseous dental implant, Int. J. Oral. Implant. 1987, 4(2), 41-46
  9. Anneroth, G., Ericson, T., Johaiisson, L, Momstad, a, Ryberg, M., Skoglund, A. and Stegmayr, B. Comprehensive medical examination of a group of patients with alleged adverse effects from dental amalgam,. Acta. Odontol. Scand. 1992, 50(2), 101-111
  10. Babbush, C. A. Endosseous blade implants: A research review. J. Oral. Surg. 1972, 30(3), 168-175
  11. Pilliar, R. M., Lee, J. M, and Maniatopoulus, C. Observations on the effects of movement on bone in growth into porous surfaced implants. Clin. Orthop. 1986, 208, 108-113
  12. Dahlin, C., Sennerby, L., Lekholm, U., Linde, A. and Nyman, S. Generation of new bone around titanium implants using a membrane technique: an experimental study in rabbits, hit J. Oral. Maxillofacial. Implants. 1989, 4(1), 19-25
  13. Schwartz, Z., Shani, J., Soskolne, W. A., Touma, H., Amir, D. and Sela, J. Uptake and biodistribution of technetium-99m- MD32P during rat tibial bone repair. J. Nuclear. Med. 1993, 34(1), 104-108
  14. Zarh, G. A. and Synington, J. M Osseointegrated dental implants, Preliminary report on a replication study. J. Prosth. Dent. 1983, 50(2), 271-276
  15. Brunski, J. B. Forces on dental implants and interfacial stress transfer, Proceedings of the second international congress on tissue integration in oral, otthopedic and maxilldadal reconstruction. Rochester, Minnesota. 1990, 108-124
  16. Mayahara, H., Ito, T., Nagai, H., Miyajima, H., Tsukuda, R., Taketomi, S., Mizoguchi, J. and Kato, K. In vivo stimulation of endosteal bone formation by basic fibroblast growth factor in rats. Growth Factors. 1993, 9(1), 73-80
  17. Schnitman, P. A. and Schulinan, L. R Dental implants; Benefits and risk and NIH-Harvaid concensus development conference. US department of health and human science. 1979, 1-351
  18. Schatzker, J. G., Horne, J. G. and Sumner-smith, G. The effects of movement on the holding power of screws in bone. din. Orthop. 1975, 111, 257-262
  19. Albreksson, T. and Sennerby, L. Direct bone anchorage of oral implants; Qinical and experimental consideration of the concept of osseointegration. Int. J. Prosthdont. 1990, 3(1), 30-41
  20. Newman, M. G. and Flenuniiig, T. F. Pehodontal considerations of implants and implant-associated miciobiota. J. Dent. Educ. 1988, 52(12), 737-744
  21. Lazzara, R. J. Use of osseointegrated irnplants for replacement of single teeth, Compendium. 1989, 10(10), 550-554