Anesthetic Effects of Zoletil on Japanese Macaque (Macaca fuscata) Reared in Zoological Garden

동물원에서 사육중인 Japanese Macaque (Macaca fuscata)에서 Zoletil 마취에 관한 연구

  • Lee, Jae-il (College of Veterinary Medicine, Chungnam National University) ;
  • Lee, Soo-Jin (College of Veterinary Medicine, Chungnam National University) ;
  • Hong, Sung-hyeok (College of Veterinary Medicine, Chungnam National University) ;
  • Shin, Nam-shik (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Duck-hwan (College of Veterinary Medicine, Chungnam National University) ;
  • Park, Chang-sik (Division of Animal Science & Resources, Research Center for Transgenic Cloned Pigs, Chungnam National University) ;
  • Jun, Moo-hyung (College of Veterinary Medicine, Chungnam National University) ;
  • Cho, Jong-min (College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Young-suk (College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Myung-cheol (College of Veterinary Medicine, Chungnam National University)
  • 이재일 (충남대학교 수의과대학) ;
  • 이수진 (충남대학교 수의과대학) ;
  • 홍성혁 (충남대학교 수의과대학) ;
  • 신남식 (서울대학교 수의과대학) ;
  • 김덕환 (충남대학교 수의과대학) ;
  • 박창식 (충남대학교 동물자원학부, 형질전환복제돼지연구센터) ;
  • 전무형 (충남대학교 수의과대학) ;
  • 조종민 (충남대학교 수의과대학) ;
  • 김영석 (충남대학교 수의과대학) ;
  • 김명철 (충남대학교 수의과대학)
  • Accepted : 2003.04.24
  • Published : 2003.06.30


To evaluate the effects of Zoletil (tiletamine- zolazepam) that have been widely used for the chemical restraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque(Macaca fuscata), this study was carried out. Zoletil was administered by intramuscular injection. Evaluation of temperature, heart rate, respiration rate and blood gas analysis were performed before administration and at 1, 10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded. There was no significant difference in heart rate, $PCO_2$, $PO_2$ after Zoletil administration rut temperature, respiraticn rate, pH were significant difference compared with these of Mere administration. The induction time was $2.5{\pm}1.0min$ and maintenance time was $86{\pm}23.2min$. It was considered that Zoletil could be usefully used for the sedation and immobilization of Japanese macaque reared in zoological garden.


Supported by : 한국과학재단


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