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Effects of Scolopendra subspinipes multilans Herb-Acupuncture on the Carrageenan induced arthritis in rats

오공약침(蜈蚣藥針)이 Carrageenan으로 유발(誘發)된 흰 쥐의 관절염(關節炎)에 미치는 영향(影響)

  • Yu, Won-Bok (Department of Oriental Medicine, College of Oriental, Semyung University) ;
  • Soh, Kyeong-Sun (Department of Oriental Medicine, College of Oriental, Semyung University) ;
  • Jeong, Chan-Gil (Department of Oriental Medicine, College of Oriental, Semyung University) ;
  • Kim, Kwang-Ho (Department of Oriental Medicine, College of Kyung Hee University)
  • 류원복 (세명대학고 한의과대학) ;
  • 소경순 (세명대학고 한의과대학) ;
  • 정찬길 (세명대학고 한의과대학) ;
  • 김광호 (경희대학교 한의과대학 예방의학교실)
  • Published : 2004.12.30

Abstract

This study was designed to check of Scolopendra subspinipes multilans Herb-Acupucture on effect of anti-inflammtory function, anti-febrile function and analgestic function in carrageenan-induced arthritic rat. Each of 8 rat were classified into control, sample group. Control group were inject by normal saline and Sample group were injected by Scolopendra subspinipes multilans. Herb-Acupuncture. After elicitating edema and inflammation of Sprgue Dawely(SD) rats by injection of 1% Carrageenan 0.1ml, then the rate of increase of paw edema, CRP, ESR, WBC were checked and rectal-temperature, topical temperature was checked about anti-febrile. writhing syndrome was checked about analgesic. The results were as follows 1. In the sample group, the rate of increase of paw edema was significantly decreased as compared with thatof control group(P<0.05) 2. In the sample group, the rectal-temperature was non-significantly decreased as compared with that of control group (P<0.05) 3. In the sample group, CRP and WBC was significantly decreased as compared with that of control group, but ESR was not.(P<0.05) 4. In the sample group, opical-temperature was significantly decreased as compared with that of control group (P<0.05) 5. In the sample group, analgestic function was not sigiflcntly effected as compared with that of control group(P<0.05) According to the above result, it can be concluded Scolopendra subspinipes multilans Herb-Acupucture showed the treatment effects on the artifical arthritis resulted from carrageenan in rat and it is suggested that more interest and study in the mechanism and clinical use were needed.

Keywords

References

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