Effects of Instant Coffee on Weight, Plasma Lipids, Leptin, and Fat Cell Size in Rats Fed on a High Fat Diet

커피를 고지방식이에 첨가하였을 때 흰쥐의 체중, 혈중 지질 및 leptin 농도와 지방세포의 크기에 미치는 영향

  • Kang, Keum-Jee (Department of Food and Nutrition, Duksung Women's University) ;
  • Choi, Sung-Sook (Department of Food and Nutrition, Duksung Women's University) ;
  • Han, Hye-Kyoung (Department of Food and Nutrition, Duksung Women's University) ;
  • Kim, Kwan-Jung (Dongsuh Food Cooperation) ;
  • Kwon, So-Young (Department of Food and Nutrition, Duksung Women's University)
  • 강금지 (덕성여자대학교 자연과학대학 식품영양학과) ;
  • 최성숙 (덕성여자대학교 자연과학대학 식품영양학과) ;
  • 한혜경 (덕성여자대학교 자연과학대학 식품영양학과) ;
  • 김관중 (동서식품주식회사) ;
  • 권소영 (덕성여자대학교 자연과학대학 식품영양학과)
  • Published : 2004.06.30


Effects of instant coffee on weight, plasma lipids, leptin levels, and fat cell size in high-fat diet-fed rats were investigated, Twenty-four male Sprague-Dawley rats, fed experimental diet containing 40% total dietary fat and 0, 0.6, 1.2, and 2.4% (w/w) instant coffee for 6 weeks, were divided into four experimental groups (n = 6). Feed efficiency ratio of 0.6% coffee group was higher than control group. Weight gain, organ weights, free fatty acid level, and fat cell size were not significantly different among groups. Triglyceride, total cholesterol, HDL-cholesterol, and leptin levels in plasma were significantly higher in 0.6% coffee group than control group. No significant difference in feed efficiency ratio, triglyceride, and leptin levels were found between control and 2.4% coffee group. These results suggest instant coffee may not have effect on obesity.


instant coffee;weight gain;lipid;leptin;fat cell size


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