Gastroprotective Effect of Korean Rice-Wine (Yakju)

한국 전통약주의 위보호 효과

  • 김승진 ((주)국순당 부설연구소) ;
  • 백지영 ((주)켐온 전임상연구센터) ;
  • 박찬구 ((주)켐온 전임상연구센터) ;
  • 김계원 ((주)국순당 부설연구소)
  • Published : 2004.10.31

Abstract

Gastroprotective effects of Korean rice-wine (Yakju) in two types of acute experimental gastric ulcer induced in rats and in mice were evaluated. Korean rice-wine were administered to 24-hr fasted rats 30 min before administration of 60% EtOH in 150 mM HCl or absolute ethanol. Korean rice-wine prevented formation of gastric ulcers induced by 60% EtOH in 150 mM HCl at oral doses of 250-1,000mg/kg and reduced gastric ulcers induced by absolute ethanol at oral doses of 62.5-1,000mg/kg, and inhibitory effect against 30% alcohol treatment for 7 days (twice/day). These results suggest Korean rice-wine have inhibitory effects on gastric lesion and ulceration.

Keywords

gastroprotective effect;Korean rice-wine;yakju;repeatedly alcohol administration effect;gastric ulceration

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