Weight Reduction and Lipid Lowering Effects of Kimchi Lactic Acid Powder in Rats Fed High Fat Diets

고지방식이를 섭취한 흰쥐에서 김치유산균분말의 비만 억제 및 지질 저하 효과

  • Kwon, Jin-Young (Department of Food Science and Nutrition/Kimchi Research Institute, Pusan National University) ;
  • Cheigh, Hong-Sik (Department of Food Science and Nutrition/Kimchi Research Institute, Pusan National University) ;
  • Song, Yeong-Ok (Department of Food Science and Nutrition/Kimchi Research Institute, Pusan National University)
  • 권진영 (부산대학교 식품영양학과) ;
  • 최홍식 (부산대학교 식품영양학과) ;
  • 송영옥 (부산대학교 식품영양학과)
  • Published : 2004.12.31

Abstract

Effects of kimchi lactic acid powder (KL) on weight reduction and lipid-lowering activities were studied using rats fed high fat diet. Spraque Dawley (40 rats) were fed 20% (w/w) high fat diet far 8 weeks to induce obesity and divided equally into normal diet (ND), high fat diet (HFD), and 10 and 20% KL-added groups. Body weight of HFD was 150% (p<0.01) of ND, while those of HFK10 and HFK20 decreased by 13 and 15% compared to HFD, respectively (p<0.01). Amounts of visceral fats for HFK10 and HFK20 were decreased by 42 and 48% compared to that of HFD (198% of ND), respectively (p<0.01). B had greater effect on reducing visceral fats than body weight. Plasma triglyceride (155%), cholesterol (129%), and LDL (161%) concentrations of HFD, which had been significantly increased compared to ND, dropped by 26, 9, and 8% (p<0.01) in HFK10, and 35, 17, and 33% (p<0.05) in HFK20, respectively. Decreased HDL by high fat diet was re-increased by KL supplementation. KL showed lipid-lowering and liver-protecting effects in liver possibly by interrupting lipid absorption in the intestine either by absorbing lipids in their cell walls or degrading them rapidly. Increased excretion of TG and cholesterol in feces of HFK10 and HFK20 indicates KL might have similar role to dietary fiber.

Keywords

kimchi lactic acid;high fat diet;obesity;cholesterol;triglyceride

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