Position Control of Capsule Filled with Magnetic Fluid for Targeted Drug Delivery System

지적투약시스템을 위한 자성유체 캡슐의 위치 제어

  • 안창호 (부산대학교 대학원) ;
  • 남윤주 (부산대학교 대학원) ;
  • 박명관 (부산대학교 기계공학부 및 기계기술연구소)
  • Published : 2004.08.01


In this paper, in order to apply magnetic fluid with superparamagnetic property as the substitute of ferromagnetic materials, physical properties of magnetic fluid are investigated. A targeted drug delivery system using a capsule filled magnetic fluid is proposed where a magnetic fluid capsule and cylinders are considered as a drug and vital organs, respectively. The dynamic governing equation of this system first is derived. Fluid viscosity, clearance between a cylinder and a magnetic fluid capsule, and levitation height with respect to different cylinder height are considered as major parameters to evaluate dynamic characteristics of the system. The experiments and simulations for the position control of the magnetic fluid capsule in various cylinders are conducted using PID controller. The results show that magnetic fluid with the superparamagnetic property can be applied to a targeted drug delivery system.


  1. Mitsuya, Y., Abe, T. and Matsunaga, S., 1993, 'Novel Mechanism of Self-Injecting Magnetic Fluid Seal Applying Switch of Magnetic Force Direction on Yoke Surface,' J. Magn. Magn. Mater., Vol. 122, pp. 415-419
  2. Mitsuya, Y., Tomita, K. and Hosoya, M., 1993, 'Experimental Study on Splashing Characteristics of Magnetic Fluid in a Magnetic Fluid Seal,' J. Magn. Magn. Mater., Vol. 122, pp. 420-423
  3. Vislovich A. N., Medvedev, V. F., Dmitrichenko, A. S., Bondarenko, G A. and Morozov, V. N., 1993, 'A Magnetic Fluid Gate as a New Element in Sealing Technology,' J. Magn. Magn. Mater., Vol. 122, pp. 411-414
  4. Fukuda, H., Ueno, K., Kamiyama, S. and Oyama, T., 1998, 'Study on Active Damper with a Magnetic Fluid,' Int. J. JSME, B, Vol. 41, No.4
  5. Kamiyama, S., 1999, 'Appications of Oscillatory Flow of Magnetic Fluid as Active Damper and Actuator,' Int. J. Modern Physics, B, Vol. 13, No. 14, 15 and 16, pp. 2213-2220
  6. Seo, J. W. and Park, S. J., 1999, 'An Experimental Study Light Modulator Using Magnetic Fluid for Display Application,' J. Magn. Magn. Mater., Vol. 192, pp. 499-504
  7. Umehara, N. and Kato, K., 1993, 'Fundamental Properties of Magnetic Fluid Griding with a Floating Polisher,' J. Magn. Magn. Mater., Vol. 122, pp. 428-431
  8. Bashtovoi, V. G, Challant, G and Volkova, O. Yu., 1993, 'Boiling Heat Transfer in Magnetic Fluids,' J. Magn. Magn. Mater., Vol. 122, pp. 305-308
  9. Calarasu, D., Cotae, C. and Olaru, R., 1999, 'Magnetic Fluid Brake,' J. Magn. Magn. Mater., Vol. 201, pp. 401-403
  10. Jeon, D. Y., Park, C. H. and Yoo, J. Y., 1998, 'Semi-Active Vibration Control using an MR Damper,' J. Cont. Automat. Syst., Vol. 4, No.1, pp. 26-31
  11. Hong, S. R. and Choi, S. B., 1999, 'Performance Comparison Between ER and MR Clutches with Same Gap Size,' J. Korean Soc. Mech. Eng.(Part A),Vol. 23, No.6, pp. 1055-1064
  12. Kim, J. H. and Oh, J. H., 2000, 'A Study on the Design of Valve Mode MR Damper Using Permanent Magnet,' J. Korean Soc. Precision Eng., Vol. 17, No. 10, pp. 69-76
  13. Nam, M. H. 2000, 'Performance Characteristics of Seat Damper Using MR Fluid,' J. Korean Soc. Mach. Tool Eng., Vol. 9, No.5, pp. 127-134
  14. Lee, W. S., Kim, T. G, Hur, N. K. and Jeon, D. Y., 2000, 'Design Analysis and Experimental Evaluation of an MR Fluid Clutch,' J. Korean Soc. Mech. Eng., Vol. 24, No.8, pp. 2143-2150
  15. Kim, K. D., Sim, W. C., Jeon, D. Y. and Choi, B. K., 2000, 'A Controllable Micro Damper Using MagnetoRheological Fluids,' J. Korean Soc. Precision Eng., Vol. 17, No.8, pp. 41-45
  16. Rosensweig, R. E., 1997, Ferrohydrodynamics, Dover Publications, Inc., Mineola, New York
  17. Ginder, J. M. and Ceccio, S. L., 1995, 'The Effect of Electrical Transients on the Shear Stresses in Elctrorheological Fluids,' J. Rheology, Vol. 39, No.1, pp.211-234

Cited by

  1. Study of Natural Convection of Magnetic Fluid in Cubic Cavity vol.37, pp.7, 2013,