Control of canine respiratory and diarrheal disease using egg yolk antibodies I. Induction of antibody in hens immunized with combined antigens of Bordetella bronchiseptica, parvovirus and canine distempervirus

난황면역제를 이용한 개 주요 소화기 및 호흡기질병 방제에 관한 연구 I. 개 보데텔라, 파보바이러스 및 개디스템퍼 항원의 닭에서의 면역반응

  • Lee, Hee-soo (National Veterinary Research and Quarantine Services) ;
  • Kim, Jong-man (National Veterinary Research and Quarantine Services) ;
  • Woo, Seng-ryong (National Veterinary Research and Quarantine Services) ;
  • Jung, Byeong-yeal (National Veterinary Research and Quarantine Services) ;
  • Cho, Yun-Sang (National Veterinary Research and Quarantine Services) ;
  • Tark, Dong-seob (National Veterinary Research and Quarantine Services) ;
  • Lim, Sook-kyoung (National Veterinary Research and Quarantine Services) ;
  • Yoo, Han sang (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University) ;
  • Yoon, Yong-dhuk (Green Cross Veterinary Science Institute) ;
  • Huh, Woo (Dae Sung Microbiology Laboratory) ;
  • Mun, Young-sik (Dae Sung Microbiology Laboratory) ;
  • Oh, Jin-sik (Green Cross Veterinary Science Institute)
  • 이희수 (국립수의과학검역원) ;
  • 김종만 (국립수의과학검역원) ;
  • 우승룡 (국립수의과학검역원) ;
  • 정병열 (국립수의과학검역원) ;
  • 조윤상 (국립수의과학검역원) ;
  • 탁동섭 (국립수의과학검역원) ;
  • 임숙경 (국립수의과학검역원) ;
  • 유한상 (서울대학교 수의과대학 및 농생명공학부) ;
  • 윤용덕 (녹십자수의연구소) ;
  • 허원 (대성미생물연구소) ;
  • 문영식 (대성미생물연구소) ;
  • 오진식 (녹십자수의연구소)
  • Accepted : 2004.02.20
  • Published : 2004.03.31


This study was carried out to produce IgY against B. bronchiseptica, parvovirus and distemper virus that are major pathogens in alimentary and/or respiratory diseases of dogs. In the comparison of adjuvants, ISA70 was the best in the rapid induction and maintence of antibody titers. Agglutination antibody titers against B. bronchiseptica were 1:1,280 ~ 1:10,240 in sera and 1:160 ~ 1:1,280 in egg yolk. Hemagglutination inhibition(HI) titers against parvovirus in sera and egg yolk were 1:80 ~ 1:320 and 1:64 ~ 1:256, respectively. Virus neutralization titers against canine distemper was 1:8 ~ 1:64 in sera and egg yolk. These results suggested that egg yolk antibody titers could be variable according to a sort of adjuvant and antigens of the pathogens.


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