Effects of teat dipping disinfectant containing biodegradable iodophor microspheres on preventing dry period intramammary infection in dairy cows

생분해성 iodophor microsphere 함유 유두침지 소독제의 건유기 젖소에서의 유방내 신규감염 예방 효과

  • Hwang, Cheol-Yong (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Jong-Min (College of Veterinary Medicine, Seoul National University) ;
  • Youn, Hwa-Young (College of Veterinary Medicine, Seoul National University) ;
  • Han, Bo (College of Veterinary Medicine, China Agricultural University) ;
  • Han, Hong-Ryul (College of Veterinary Medicine, Seoul National University)
  • 황철용 (서울대학교 수의과대학) ;
  • 김종민 (서울대학교 수의과대학) ;
  • 윤화영 (서울대학교 수의과대학) ;
  • 한박 (중국 농업대학교 동물의학원) ;
  • 한홍율 (서울대학교 수의과대학)
  • Accepted : 2003.12.30
  • Published : 2004.03.31


1% iodophor loaded microspheres of PLGA (Poly[DL-Lactide-co-Glycolide]) were prepared by solvent evaporation method and were applied to the cows on dry period for evaluating it's preventive effects on intramammary infections. The morphology of the microspheres were evaluated using scanning electron microscopy and their releasing patterns were investigated. On investigating idophor releasing patterns of the microsphere, burst releasing pattern was detected until 2 days after in vitro incubation and sustained releasing was observed until 4 weeks. In field trial of teat dipping solution containing idophor loaded microspheres in dry cows showed significant preventive effects of intramammary infection caused by S. aureus, S. agalactiae, coagulase negative Staphylococci and coliform bacteria (p<0.05).


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