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Effect of Dietary Iron and Exercise on Heme Biosynthesis and Lipid Metabolism of Rats

철분과 운동이 흰쥐의 헴 생합성과 지질 대사에 미치는 영향

  • 최지영 (용인대학교 식품영양학과) ;
  • 김혜영 (용인대학교 식품영양학과)
  • Published : 2005.06.01

Abstract

This study was peformed to investigate the effect of dietary iron and exercise on heme biosynthesis and lipid metabolism of rats. Rats were divided into 4 groups according to dietary iron supplement (Fe-,5 ppm vs. Fe+, 50 ppm) and exercise status (control us exercise). The experiment continued for 8 weeks. Regular treadmill exercise ($6^{\circ}$, 28 m/min, 30 min duration, 5 days/week) was given to exercise groups. The aminolevulinate dehydrase activity of red blood cell, the marker of heme biosynthesis, was significantly increased in the exercise group. Regular aerobic exercise reduced body weight and epidydimal fat pad gain. Regular exercise also significantly decreased the plasma triglyceride, cholesterol and HDL-cholesterol of the rats. Meanwhile, the iron deficiency decreased the hematocrit and hemoglobin concentration and increased the accumulation of liver cholesterol.

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