Antimicrobial and Antitumor Activities of Seed Extracts of Camellia sinensis L.

차나무 종자 추출물의 항균활성 및 항종양활성

  • 윤원호 (서일대학 식품가공과) ;
  • 최재훈 (건국대학교 동물자원연구센터) ;
  • 이경호 (코오롱중앙기술원) ;
  • 김창한 (건국대학교 동물자원연구센터)
  • Published : 2005.02.28


Antimicrobial and antitumor activities of Camellia sinensis L seed extracts were investigated. Seed extracts showed antifungal activities against Candida albicans IFO 1594 and Cryptococcus neoformans. Inhibition zone of 20 mm was shown by 70% ethanol extract against C. albicans IFO 1594 at 100 mg/mL. Antifungal activity of seed extract was not decreased by heating at 80 and $100^{\circ}C$ for 30 min or at $121^{\circ}C$ for 15 min, indicating heat-stability of seed component. Growth-inhibitory effects were observed in 70 and 10% of tumor cell line SK-OV-3 and normal ceil line NIH/3T3 at $50{\mu}g/mL$, respectively.


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