Analysis of Variability Factors in Establishing Pesticide Residue Limits on Food Crops

농산물중 농약잔류 허용기준 설정시의 변이계수 분석

  • Published : 2005.06.30


In establishing legal limits of pesticide residues, various default values are employed to compensate for unavoidable variability in data. Because permissible errors in residue analysis reach ${\pm}30-40%$ RSD, maximum residue limits (MRLs) follow geometric progression. According to 5-yr period JMPR reports, variability factor (ratio of highest to median values) in field residue trials was 3.8-fold in 486 crop-pesticide combinations and round-up effort from highest residue to MRL was 1.5-fold, whereas regulatory margin (ratio of MRL to highest residue) used in Korea was 4.8-fold in 822 crop-pesticide combinations; Korean MRLs will be set at higher levels as compared with Codex limits if these margins are employed. Validation studies to compare and harmonize Korean and Codex MRLs of pesticide residues on food crops should be undertaken.


pesticide residue limits;variability factor;food crops


  1. Orriss GD. Current strategy on food risk assessment and management in FAO/WHO. pp. 3-14. In: Risk Assessment and Management of Environmental Contaminants in Food. November 27, KFDA, Seoul, Korea. Korea FDA/UNDP, Seoul, Korea (1998)
  2. JMPR. Reports of the Joint FAO/WHO Meeting of Experts on Pesticide Residues. FAO/WHO (1998-2002)
  3. FAO. Manual on the Submission and Evaluation of Pesticide Residue Data for the Estimation of Maximum Residue Levels in Food and Feed, UN FAO, Rome, Italy (2002)
  4. Lee SR, Lee MG. Present status and remedial actions with regard to legal limits of pesticide residues in Korea. Korean J. Environ. Agric. 20: 34-43 (2001)
  5. FAO/WHO. Report of the Tenth Session of the Codex Committee on Pesticide Residues. Alinorm 79/24, para. 198 (1978)
  6. Elgar KE. The variability of residue results, with particular reference to the Codex study on organochlorines in butterfat. p. 54 In: Pesticide Residues. A Contribution to Their Interpretation, Relevance and Legislation. Frehse H, Geissbuehler H (ed). Pergamon, New York, USA (1979)
  7. Lee MG, Lee SR. Studies to improve the tolerance setting system of pesticides in foods. Report of Korea Food & Drug Administration, Seoul, Korea (2004)
  8. Ekstrom G, Akerblom M. Pesticide management in food and water safety. International contributions and national approaches. Rev. Environ. Contam. Toxicol. 114: 23-55 (1990)
  9. Frehse H, Timme G. Quantitative residue analytical reliability; Beatitude through application of latitude. Residue Rev. 73: 27-47 (1980)
  10. CCPR. Reports of the Codex Committee on Pesticide Residues. FAO/WHO (1998-2002)
  11. Rural Development Administration. Guidelines for Testing Pesticide Residues on Crops. RDA Notice No. 2003-7, Supplement Table 8, Korea. (2003)
  12. FAO/WHO. Pesticide residues in food. FAO Agricultural Studies No. 87, Rome; WHO Tech. Rep. Ser. No. 474, Geneva (1971)
  13. UNEP, ILO, WHO. Assessing Human Health Risks of Chemicals - Derivation of Guidance Values for Health-based Exposure Limits. Environmental Health Criteria 170, WHO, Geneva, 73 pp. (1994)
  14. Expert Committee on Pesticide Residues, Korea FDA. Documents in Establishing MRLs of Pesticide Residues on Food Crops (1999-2003)
  15. FAO/WHO. Report of the Ninth Session of the Codex Committee on Pesticide Residues. Alinorm 78/24, para.181 (1977)
  16. FAO/WHO. Pesticide residues in food. FAO Agricultural Studies No. 92, Rome; WHO Tech. Rep. Ser. No. 545, Geneva (1974)
  17. Lee SR. Food Safety and Toxicology. Ewha Woman's Univ. Press, Seoul, Korea, pp. 51-90 (1993)