Evaluation of the Estrogenic and Antioxidant Activity of Some Edible and Medicinal Plants

식용 및 약용자원의 에스트로젠 활성과 항산화능 평가

  • Choi, Sun-Young (Department of Food and Nutrition, Seoul National University) ;
  • Lim, Sun-Hye (Food Function Research Division, Korea Food Research Institute) ;
  • Kim, Ji-Sun (Food Function Research Division, Korea Food Research Institute) ;
  • Ha, Tae-Youl (Food Function Research Division, Korea Food Research Institute) ;
  • Kim, Sung-Ran (Food Function Research Division, Korea Food Research Institute) ;
  • Kang, Kyung-Sun (Department of Veterinary Public Health, Seoul National University) ;
  • Hwang, In-Kyeong (Department of Food and Nutrition, Seoul National University)
  • 최선영 (서울대학교 식품영양학과) ;
  • 임선혜 (한국식품연구원 식품기능연구본부) ;
  • 김지선 (한국식품연구원 식품기능연구본부) ;
  • 하태열 (한국식품연구원 식품기능연구본부) ;
  • 김성란 (한국식품연구원 식품기능연구본부) ;
  • 강경선 (서울대학교 수의학과) ;
  • 황인경 (서울대학교 식품영양학과)
  • Published : 2005.08.31


Estrogenic and antioxidant activities of ethanol extracts of 45 edible and medicinal plants were evaluated by ${\beta}-galactosidase$ assay, and DPPH radical scavenging assay, and TBARS inhibition rate, respectively. Total polyphenol contents were in the range of 8.6 (Panax notoginseng Buck F.H. Chen.)-594.7 (Amomum globosum Loureiro) mg/g. Direct correlation between the DPPH radical scavenging activity and polyphenol content $(r^2=0.61)$ was established through simple regression analysis, whereas no correlation was observed between TBARS inhibition rate or ${\beta}-galactosidase$ activity and polyphenol content. Among medicinal plants screened, Glycyrrhiza glabra L. and Rheum undulatum L. showed strong antioxidant and estrogenic activities. Results of this study could be used as fundamental data for selecting potential phytoestrogen candidates.


antioxidant activity;estrogenic activity;edible and medicinal plant;${\beta}-galactosidase$ assay


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