Determination of benzophenone in water, soil and sediment by gas chromatography/mass spectrometry

기체크로마토그래피/질량분석기에 의한 수질, 토양 및 저질 시료중의 benzophenone 분석법에 관한 연구

  • Received : 2005.01.25
  • Accepted : 2005.03.08
  • Published : 2005.04.25


Benzophenone (BP) which is one of endocrine disrupting chemicals is suspected to contaminate waters (river, lake and industrial drainage) and soils (ground soil and sediment). Analytical method for determination of BP in soil and water was developed by gas chromatography/mass spectrometry. Water sample (100 mL) was extracted with n-hexane, and soil (10 g) was extracted with methanol and n-hexane. Recovery for BP was >71.4% in water and 86.5-94.7% in soil with coefficient variation of less than 19.8%. Calibration curves showed a good linearity ($r^2$ >0.998). In water, soil and sediment collected at nation-wide sites, BP was detected at 5 sites among 43 water sites at the concentration range of 30-200 ng/L. No BP was found in the soil and sediment samples. It is suggested that this method will be useful to the determination of BP in the environmental matrices such as waters, soils and sediments in minute quantities.


benzophenone;endocrine disruptor;water;soil;gas chromatography/mass spectrometry


  1. V. Vanquer and C. Rodriguez and C. Coiffard and L. J. Coiffard and Y. De. Roeck-Holtzhauer, J. Chromatogr. A., 832(1-2), 273-277(1999)
  2. M. Ricking, J. Schwarzbauer, and S. Franke, Water Res., 37, 2607-2617(2003)
  3. Y. W. Eo, H. M. Park, J. C. Ryu, J. K. Hong, Y. M. Kim and K. B. Lee, Environmental Analysis, 3(2), 109-115(2000)
  4. H. K. Lee, O. S. Kwon and J. C. Ryu, Kor. J. Environm. Toxicol., 15(1,2) 45-51(2000)
  5. O. S. Kwon, E. Y. Kim and J. C Ryu, Kor. J. Environ. Toxicol., 16(3), 121-126(2001)
  6. F. Guan and H. Seno and A. Ishii and K. Watanabe and T. Kumazawa and H. Hattori and O. Suzuki, J. Anal. Toxicol., 23(1), 54-61(1999)
  7. H. Park, M. R. Agustin, H. M. Park, J. C. Ryu, B. J. Lim and K. B. Lee, J. Korean Soc. Environ. Analysis, 6(3), 169-177(2003)
  8. M. E. Salvucci and K. Rajagopalan and G. Sievert and B. E. Haley and D. S. Watt. J. Biol. Chem., 268 (19), 14239-14244(1993)
  9. National Institute for Environmental Studies (NIES), 'Analytical methods for endocrine disruptors', Japan., 1998
  10. J. Wang and S. Bauman and R. F. Colman. J. Biol. Chem., 275(8), 5493-5503(2000)
  11. S. Jobling and T. Reynolds and R. White and M. G. Parker and J. P. Sumpter, Environmental Health Perspective., 103(6), 582-587(1995)
  12. A. K. Krainev and R. I. Viner and D. J. Bigelow, D. J. Free Radic, Biol. Med., 23(7), 1009-1020 (1997)
  13. L. Castle and C. P. Offen and M. J. Baxter and J. Gilbert, Food. Addit. Contam. 14(1), 35-44(1997)
  14. O. S. Kwon, H. K. Rhee and J. C. Ryu, Environmental Analysis, 3(1), 1-5(2000)
  15. O. S. Kwon, E. Y. Kim and J. C. Ryu, Analytical Science and Technology, 16(1), 59-69(2003)
  16. G. Potard and C. Laugel and A. Baillet and H. Schaefer and J. P. Mart, Int. J. Pharm., 189(2), 249-260(1999)