Systemic Aspergillosis associated with bovine viral diarrhea virus infection in Korean native calves

한우송아지의 BVD바이러스 감염과 Aspergillus fumigatus의 복합감염

  • Jean, Young Hwa (National Veterinary Research & Quarantine Service) ;
  • Kim, Jae Hoon (Department of Veterinary Medicine, Jeju National University) ;
  • Kim, Dae Yong (College of Veterinary Medicine, Seoul National University) ;
  • Jeong, Soon Wuk (College of Veterinary Medicine, Konkuk University) ;
  • Moon, Oun Kyong (National Veterinary Research & Quarantine Service) ;
  • Cho, Doo Youn (Department of Veterinary Pathology, Louisiana State University)
  • Accepted : 2004.12.09
  • Published : 2005.03.25


Systemic aspergillosis were outbroken of 17 Korean native calves at livestock farm in Kyunggi province. Two 3 months old calves were died after having diarrhea, coughing, dyspnea, nasal discharge, and abdominal breathing. These calves were diagnosed of aspergillosis as multifocal to coalescing pyogranulomatous inflammation with intralesional aspergillus infiltration at liver, kidney, spleen, heart, lymph nodes, lungs, intestine and cerebrum. Aspergillus fumigatus was cultured from the affected tissues. And the small intestine was positive against bovine viral diarrhea (BVD) virus on FA test. We considered that the secondary fungal infections killed the calves after BVD virus infection primarily.


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